


Particle accelerator projects like the Large Hadron Collider (LHC) don’t just smash particles - they also power the invention of some of the world’s most impactful technologies. A favorite example is the world wide web, which was developed for particle physics experiments at CERN.
Tech designed to unlock the mysteries of the universe has brutally exacting requirements – and it is this boundary pushing, plus billion-dollar budgets, that has led to so much innovation.
For example, X-rays are used in accelerators to measure the chemical composition of the accelerator products and to monitor radiation. The understanding developed to create those technologies was then applied to help us build better CT scanners, reducing the x-ray dosage while improving the image quality.
Stories like this are common in accelerator physics, or High Energy Physics (HEP). Scientists and engineers working in HEP have been early adopters and/or key drivers of innovations in advanced cancer treatments (using proton beams), machine learning techniques, robots, new materials, cryogenics, data handling and analysis, and more.
A key strand of HEP research aims to make accelerators simpler and cheaper. A key piece of infrastructure that could be improved is their computing environments.
CERN itself has said: “CERN is one of the most highly demanding computing environments in the research world... From software development, to data processing and storage, networks, support for the LHC and non-LHC experimental programme, automation and controls, as well as services for the accelerator complex and for the whole laboratory and its users, computing is at the heart of CERN’s infrastructure.”
With annual data generated by accelerators in excess of exabytes (a billion gigabytes), tens of millions of lines of code written to support the experiments, and incredibly demanding hardware requirements, it’s no surprise that the HEP community is interested in quantum computing, which offers real solutions to some of their hardest problems.
As the authors of this paper stated: “[Quantum Computing] encompasses several defining characteristics that are of particular interest to experimental HEP: the potential for quantum speed-up in processing time, sensitivity to sources of correlations in data, and increased expressivity of quantum systems... Experiments running on high-luminosity accelerators need faster algorithms; identification and reconstruction algorithms need to capture correlations in signals; simulation and inference tools need to express and calculate functions that are classically intractable.”
The HEP community’s interest in quantum computing is growing. In recent years, their scientists have been looking carefully at how quantum computing could help them, publishing a number of papers discussing the challenges and requirements for quantum technology to make a dent (here’s one example, and here’s the arXiv version).
In the past few months, what was previously theoretical is becoming a reality. Several groups published results using quantum machines to tackle something called “Lattice Gauge Theory”, which is a type of math used to describe a broad range of phenomena in HEP (and beyond). Two papers came from academic groups using quantum simulators, one using trapped ions and one using neutral atoms. Another group, including scientists from Google, tackled Lattice Gauge Theory using a superconducting quantum computer. Taken together, these papers indicate a growing interest in using quantum computing for High Energy Physics, beyond simple one-dimensional systems which are more easily accessible with classical methods such as tensor networks.
We have been working with DESY, one of the world’s leading accelerator centers, to help make quantum computing useful for their work. DESY, short for Deutsches Elektronen-Synchrotron, is a national research center that operates, develops, and constructs particle accelerators, and is part of the worldwide computer network used to store and analyze the enormous flood of data that is produced by the LHC in Geneva.
Our first publication from this partnership describes a quantum machine learning technique for untangling data from the LHC, finding that in some cases the quantum approach was indeed superior to the classical approach. More recently, we used Quantinuum System Model H1 to tackle Lattice Gauge Theory (LGT), as it’s a favorite contender for quantum advantage in HEP.
Lattice Gauge Theories are one approach to solving what are more broadly referred to as “quantum many-body problems”. Quantum many-body problems lie at the border of our knowledge in many different fields, such as the electronic structure problem which impacts chemistry and pharmaceuticals, or the quest for understanding and engineering new material properties such as light harvesting materials; to basic research such as high energy physics, which aims to understand the fundamental constituents of the universe, or condensed matter physics where our understanding of things like high-temperature superconductivity is still incomplete.
The difficulty in solving problems like this – analytically or computationally – is that the problem complexity grows exponentially with the size of the system. For example, there are 36 possible configurations of two six-faced dice (1 and 1 or 1 and 2 or 1and 3... etc), while for ten dice there are more than sixty million configurations.
Quantum computing may be very well-suited to tackling problems like this, due to a quantum processor’s similar information density scaling – with the addition of a single qubit to a QPU, the information the system contains doubles. Our 56-qubit System Model H2, for example, can hold quantum states that require 128*(2^56) bits worth of information to describe (with double-precision numbers) on a classical supercomputer, which is more information than the biggest supercomputer in the world can hold in memory.
The joint team made significant progress in approaching the Lattice Gauge Theory corresponding to Quantum Electrodynamics, the theory of light and matter. For the first time, they were able study the full wavefunction of a two-dimensional confining system with gauge fields and dynamical matter fields on a quantum processor. They were also able to visualize the confining string and the string-breaking phenomenon at the level of the wavefunction, across a range of interaction strengths.
The team approached the problem starting with the definition of the Hamiltonian using the InQuanto software package, and utilized the reusable protocols of InQuanto to compute both projective measurements and expectation values. InQuanto allowed the easy integration of measurement reduction techniques and scalable error mitigation techniques. Moreover, the emulator and hardware experiments were orchestrated by the Nexus online platform.
In one section of the study, a circuit with 24 qubits and more than 250 two-qubit gates was reduced to a smaller width of 15 qubits thanks our unique qubit re-use and mid-circuit measurement automatic compilation implemented in TKET.
This work paves the way towards using quantum computers to study lattice gauge theories in higher dimensions, with the goal of one day simulating the full three-dimensional Quantum Chromodynamics theory underlying the nuclear sector of the Standard Model of particle physics. Being able to simulate full 3D quantum chromodynamics will undoubtedly unlock many of Nature’s mysteries, from the Big Bang to the interior of neutron stars, and is likely to lead to applications we haven’t yet dreamed of.
Quantinuum, the world’s largest integrated quantum company, pioneers powerful quantum computers and advanced software solutions. Quantinuum’s technology drives breakthroughs in materials discovery, cybersecurity, and next-gen quantum AI. With over 500 employees, including 370+ scientists and engineers, Quantinuum leads the quantum computing revolution across continents.
Quantinuum is focusing on redefining what’s possible in hybrid quantum–classical computing by integrating Quantinuum’s best-in-class systems with high-performance NVIDIA accelerated computing to create powerful new architectures that can solve the world’s most pressing challenges.
The launch of Helios, Powered by Honeywell, the world’s most accurate quantum computer, marks a major milestone in quantum computing. Helios is now available to all customers through the cloud or on-premise deployment, launched with a go-to-market offering that seamlessly pairs Helios with the NVIDIA Grace Blackwell platform, targeting specific end markets such as drug discovery, finance, materials science, and advanced AI research.
We are also working with NVIDIA to adopt NVIDIA NVQLink, an open system architecture, as a standard for advancing hybrid quantum-classical supercomputing. Using this technology with Quantinuum Guppy and the NVIDIA CUDA-Q platform, Quantinuum has implemented NVIDIA accelerated computing across Helios and future systems to perform real-time decoding for quantum error correction.
In an industry-first demonstration, an NVIDIA GPU-based decoder integrated in the Helios control engine improved the logical fidelity of quantum operations by more than 3% — a notable gain given Helios’ already exceptionally low error rate. These results demonstrate how integration with NVIDIA accelerated computing through NVQLink can directly enhance the accuracy and scalability of quantum computation.

This unique collaboration spans the full Quantinuum technology stack. Quantinuum’s next-generation software development environment allows users to interleave quantum and GPU-accelerated classical computations in a single workflow. Developers can build hybrid applications using tools such as NVIDIA CUDA-Q, NVIDIA CUDA-QX, and Quantinuum’s Guppy, to make advanced quantum programming accessible to a broad community of innovators.
The collaboration also reaches into applied research through the NVIDIA Accelerated Quantum Computing Research Center (NVAQC), where an NVIDIA GB200 NVL72 supercomputer can be paired with Quantinuum’s Helios to further drive hybrid quantum-GPU research, including the development of breakthrough quantum-enhanced AI applications.
A recent achievement illustrates this potential: The ADAPT-GQE framework, a transformer-based Generative Quantum AI (GenQAI) approach, uses a Generative AI model to efficiently synthesize circuits to prepare the ground state of a chemical system on a quantum computer. Developed by Quantinuum, NVIDIA, and a pharmaceutical industry leader—and leveraging NVIDIA CUDA-Q with GPU-accelerated methods—ADAPT-GQE achieved a 234x speed-up in generating training data for complex molecules. The team used the framework to explore imipramine, a molecule crucial to pharmaceutical development. The transformer was trained on imipramine conformers to synthesize ground state circuits at orders of magnitude faster than ADAPT-VQE, and the circuit produced by the transformer was run on Helios to prepare the ground state using InQuanto, Quantinuum's computational chemistry platform.
From collaborating on hardware and software integrations to GenQAI applications, the collaboration between Quantinuum and NVIDIA is building the bridge between classical and quantum computing and creating a future where AI becomes more expansive through quantum computing, and quantum computing becomes more powerful through AI.
By Dr. Noah Berthusen
The earliest works on quantum error correction showed that by combining many noisy physical qubits into a complex entangled state called a "logical qubit," this state could survive for arbitrarily long times. QEC researchers devote much effort to hunt for codes that function well as "quantum memories," as they are called. Many promising code families have been found, but this is only half of the story.
Being able to keep a qubit around for a long time is one thing, but to realize the theoretical advantages of quantum computing we need to run quantum circuits. And to make sure noise doesn't ruin our computation, these circuits need to be run on the logical qubits of our code. This is often much more challenging than performing gates on the physical qubits of our device, as these "logical gates" often require many physical operations in their implementation. What's more, it often is not immediately obvious which logical gates a code has, and so converting a physical circuit into a logical circuit can be rather difficult.
Some codes, like the famous surface code, are good quantum memories and also have easy logical gates. The drawback is that the ratio of physical qubits to logical qubits (the "encoding rate") is low, and so many physical qubits are required to implement large logical algorithms. High-rate codes that are good quantum memories have also been found, but computing on them is much more difficult. The holy grail of QEC, so to speak, would be a high-rate code that is a good quantum memory and also has easy logical gates. Here, we make progress on that front by developing a new code with those properties.
A recent work from Quantinuum QEC researchers introduced genon codes. The underlying construction method for these codes, called the "symplectic double cover," also provided a way to obtain logical gates that are well suited for Quantinuum's QCCD architecture. Namely, these "SWAP-transversal" gates are performed by applying single qubit operations and relabeling the physical qubits of the device. Thanks to the all-to-all connectivity facilitated through qubit movement on the QCCD architecture, this relabeling can be done in software essentially for free. Combined with extremely high fidelity (~1.2 x10-5) single-qubit operations, the resulting logical gates are similarly high fidelity.
Given the promise of these codes, we take them a step further in our new paper. We combine the symplectic double codes with the [[4,2,2]] Iceberg code using a procedure called "code concatenation". A concatenated code is a bit like nesting dolls, with an outer code containing codes within it---with these too potentially containing codes. More technically, in a concatenated code the logical qubits of one code act as the physical qubits of another code.
The new codes, which we call "concatenated symplectic double codes", were designed in such a way that they have many of these easily-implementable SWAP-transversal gates. Central to its construction, we show how the concatenation method allows us to "upgrade" logical gates in terms of their ease of implementation; this procedure may provide insights for constructing other codes with convenient logical gates. Notably, the SWAP-transversal gate set on this code is so powerful that only two additional operations (logical T and S) are necessary for universal computation. Furthermore, these codes have many logical qubits, and we also present numerical evidence to suggest that they are good quantum memories.
Concatenated symplectic double codes have one of the easiest logical computation schemes, and we didn’t have to sacrifice rate to achieve it. Looking forward in our roadmap, we are targeting hundreds of logical qubits at ~ 1x 10-8 logical error rate by 2029. These codes put us in a prime position to leverage the best characteristics of our hardware and create a device that can achieve real commercial advantage.
Every year, the International Conference for High Performance Computing, Networking, Storage, and Analysis (SC) brings together the global supercomputing community to explore the technologies driving the future of computing.
At this year’s conference, from November 16th – 21st in St. Louis, Missouri, Quantinuum showcased how our quantum hardware, software, and partnerships are helping define the next era of high-performance and quantum computing.
The Quantinuum team was on-site at booth #4432 to showcase how we’re building the bridge between HPC and quantum. Folks stopped by our booth to see:
Our quantum computing experts hosted daily tutorials at our booth on Helios, our next-generation hardware platform, Nexus, our all-in-one quantum computing platform, and Hybrid Workflows, featuring the integration of NVIDIA CUDA-Q with Quantinuum Systems.
Join our team as they share insights on the opportunities and challenges of quantum integration within the HPC ecosystem:
Panel Session: The Quantum Era of HPC: Roadmaps, Challenges and Opportunities in Navigating the Integration Frontier
November 19th | 10:30 – 12:00pm CST
During this panel session, Kentaro Yamamoto from Quantinuum, will join experts from Lawrence Berkeley National Laboratory, IBM, QuEra, RIKEN, and Pawsey Supercomputing Research Centre to explore how quantum and classical systems are being brought together to accelerate scientific discovery and industrial innovation.
BoF Session: Bridging the Gap: Making Quantum-Classical Hybridization Work in HPC
November 19th | 5:15 – 6:45pm CST
Quantum-classical hybrid computing is moving from theory to reality, yet no clear roadmap exists for how best to integrate quantum processing units (QPUs) into established HPC environments. In this Birds of a Feather discussion, co-led by Quantinuum’s Grahame Vittorini and representatives from BCS, DOE, EPCC, Inria, ORNL NVIDIA, and RIKEN we hope to bring together a global community of HPC practitioners, system architects, quantum computing specialists and workflow researchers, including participants in the Workflow Community Initiative, to assess the state of hybrid integration and identify practical steps toward scalable, impactful deployment.