Quantinuum and Microsoft achieve breakthrough that unlocks a new era of reliable quantum computing
Quantinuum’s System Model H2 enabled Microsoft’s qubit-virtualization system to generate the most reliable logical qubits ever recorded, a breakthrough with wide ranging implications for everyone in quantum computing, accelerating progress and challenging current assumptions about the timeline toward large scale reliable quantum computing.
By Ilyas Khan, Chief Product Officer and Jenni Strabley, Senior Director Offering Management
Quantinuum and Microsoft have announced a vital breakthrough in quantum computing that Microsoft described as “a major achievement for the entire quantum ecosystem.”
By combining Microsoft’s innovative qubit-virtualization system with the unique architectural features and fidelity of Quantinuum’s System Model H2 quantum computer, our teams have demonstrated the most reliable logical qubits on record with logical circuit error rates 800 times lower than the corresponding physical circuit error rates.
This achievement is not just monumental for Quantinuum and Microsoft, but it is a major advancement for the entire quantum ecosystem. It is a crucial milestone on the path to building a hybrid supercomputing system that can truly transform research and innovation across many industries for decades to come. It also further bolsters H2’s title as the highest performing quantum computer in the world.
Entering a new era of quantum computing
Historically, there have been widely held assumptions about the physical qubits needed for large scale fault-tolerant quantum computing and the timeline to quantum computers delivering real-world value. It was previously thought that an achievement like this one was still years away from realization – but together, Quantinuum and Microsoft proved that fault-tolerant quantum computing is in fact a reality.
In enabling today’s announcement, Quantinuum’s System Model H2 becomes the first quantum computer to advance to Microsoft’s Level 2 – Resilient phase of quantum computing – an incredible milestone. Until now, no other computer had been capable of producing reliable logical qubits.
Using Microsoft’s qubit-virtualization system, our teams used reliable logical qubits to perform 14,000 individual instances of a quantum circuit with no errors, an overall result that is unprecedented. Microsoft also demonstrated multiple rounds of active syndrome extraction – an essential error correction capability for measuring and detecting the occurrence of errors without destroying the quantum information encoded in the logical qubit.
As we prepare to bring today’s logical quantum computing breakthrough to commercial users, there is palpable anticipation about what this new era means for our partners, customers, and the global quantum computing ecosystem that has grown up around our hardware, middleware, and software.
Collaborating to reach a new era
To understand this achievement, it is helpful to shed some light on the joint work that went into it. Our breakthrough would not have been possible without the close collaboration of the two exceptional teams at Quantinuum and Microsoft over many years.
Building on a relationship that stretches back five years, we collaborated with Microsoft Azure Quantum at a very deep level to best execute their innovative qubit-virtualization system, including error diagnostics and correction. The Microsoft team was able to optimize their error correction innovation, reducing an original estimate of 300 required physical qubits 10-fold, to create four logical qubits with only 30 physical qubits, bringing it into scope for the 32-qubit H2 quantum computer.
This massive compression of the code and efficient virtualization challenges a consensus view about the resources needed to do fault-tolerant quantum computing, where it has been routinely stated that a logical qubit will require hundreds, even thousands of physical qubits. Through our collaboration, Microsoft’s far more efficient encoding was made possible by architectural features unique to the System Model H2, including our market-leading 99.8% two-qubit gate fidelity, 32 fully-connected qubits, and compatibility with Quantum Intermediate Representation (QIR).
Thanks to this powerful combination of collaboration, engineering excellence, and resource efficiency, quantum computing has taken a major step into a new era, introducing reliable logical qubits which will soon be available to industrial and research users.
Understanding today’s error correction breakthrough
It is widely recognized that for a quantum computer to be useful, it must be able to compute correctly even when errors (or faults) occur – this is what scientists and engineers describe as fault-tolerance.
In classical computing, fault-tolerance is well-understood and we have come to take it for granted. We always assume that our computers will be reliable and fault-free. Multiple advances over the course of decades have led to this state of affairs, including hardware that is incredibly robust and error rates that are very low, and classical error correction schemes that are based on the ability to copy information across multiple bits, to create redundancy.
Getting to the same point in quantum computing is more challenging, although the solution to this problem has been known for some time. Qubits are incredibly delicate since one must control the precise quantum states of single atoms, which are prone to errors. Additionally, we must abide by a fundamental law of quantum physics known as the no cloning theorem, which says that you can’t just copy qubits – meaning some of the techniques used in classical error correction are unavailable in quantum machines.
The solution involves entangling groups of physical qubits (thereby creating a logical qubit), storing the relevant quantum information in the entangled state, and, via some complex functions, performing computations with error correction. This process is all done with the sole purpose of creating logical qubit errors lower than the errors at the physical level.
However, implementing quantum error correction requires a significant number of qubit operations. Unless the underlying physical fidelity is good enough, implementing a quantum error correcting code will add more noise to your circuit than it takes away. No matter how clever you are in implementing a code, if your physical fidelity is poor, the error correcting code will only introduce more noise. But, once your physical fidelity is good enough (aka when the physical error rate is “below threshold”), then you will see the error correcting code start to actually help: producing logical errors below the physical errors.
Quantinuum’s fault-tolerance roadmap
Today’s results are an exciting marker on the path to fault-tolerant quantum computing. The focus must and will now shift from quantum computing companies simply stating the number of qubits they have to explaining their connectivity, the underlying quality of the qubits with reference to gate fidelities, and their approach to fault-tolerance.
Our H-Series hardware roadmap has not only focused on scaling qubits, but also developing useable quantum computers that are part of a vertically integrated stack. Our work across the full stack includes major advances at every level, for instance just last month we proved that our qubits could scale when we announced solutions to the wiring problem and the sorting problem. By maintaining higher qubit counts and world class fidelity, our customers and partners are able to advance further and faster in fields such as material science, drug discovery, AI and finance.
In 2025, we will introduce a new H-Series quantum computer, Helios, that takes the very best the H-Series has to offer, improving both physical qubit count and physical fidelity. This will take us and our users below threshold for a wider set of error correcting codes and make that device capable of supporting at least 10 highly reliable logical qubits.
A path to real-world impact
As we build upon today’s milestone and lead the field on the path to fault-tolerance, we are committed to continuing to make significant strides in the research that enables the rapid advance of our technologies. We were the first to demonstrate real-time quantum error correction (meaning a fully-fault tolerant QEC protocol), a result that meant we were the first to show: repeated real-time error correction, the ability to perform quantum "loops" (repeat-until-success protocols), and real-time decoding to determine the corrections during the computation. We were the first to create non-Abelian topological quantum matter and braid its anyons, leading to topological qubits.
The native flexibility of our QCCD architecture has allowed us to efficiently investigate a large variety of fault-tolerant methods, and our best-in-class fidelity means we expect to lead the way in achieving reduced error rates with additional error correcting codes – and supporting our partners to do the same. We are already working on making reliable quantum computing a commercial reality so that our customers and partners can unlock the enormous real-world economic value that is waiting to be unleashed by the development of these systems.
In the short term – with a hybrid supercomputer powered by a hundred reliable logical qubits, we believe that organizations will be able to start to see scientific advantages and will be able to accelerate valuable progress toward some of the most important problems that mankind faces such as modelling the materials used in batteries and hydrogen fuel cells or accelerating the development of meaning-aware AI language models. Over the long-term, if we are able to scale closer to ~1,000 reliable logical qubits, we will be able to unlock the commercial advantages that can ultimately transform the commercial world.
Quantinuum customers have always been able to operate the most cutting-edge quantum computing, and we look forward to seeing how they, and our own world-leading teams, drive ahead developing new solutions based on the state-of-the-art tools we continue to put into their hands. We were the early leaders in quantum computing and now we are thrilled to be positioned at the forefront of fault-tolerant quantum computing. We are excited to see what today’s milestone unlocks for our customers in the days ahead.
For more information
- Please register for Microsoft’s upcoming Quantum Innovator Series with Quantinuum
- Visit Quantinuum InQuanto to explore this state-of-the-art chemistry platform that will soon offer reliable logical qubits
- Read Microsoft’s announcement
- See System Model H1 and H2 integrated on Azure Quantum
About Quantinuum
Quantinuum, the world’s largest integrated quantum company, pioneers powerful quantum computers and advanced software solutions. Quantinuum’s technology drives breakthroughs in materials discovery, cybersecurity, and next-gen quantum AI. With over 500 employees, including 370+ scientists and engineers, Quantinuum leads the quantum computing revolution across continents.
It is believed that unlocking answers to some of the most complex scientific and industrial problems will require the seamless integration of high-performance computing (HPC), generative AI (GenAI), and quantum computing. Toward this goal, Quantinuum, NVIDIA, and a major pharmaceutical company have successfully demonstrated the first step in a proof-of-principle framework designed to connect these three distinct computing paradigms for industrially relevant computational chemistry.
This milestone, enabled by three industry leaders and experts in their respective domains, serves as a foundational capability that could support the development of future hybrid quantum-AI workflows to help optimize industrial research and development (R&D).
The potential value is a path toward more automated, repeatable, and scalable workflows for translating chemistry problems into executable quantum programs—capabilities that could eventually make hybrid computing easier to deploy in industrial R&D.
The GenQAI Framework
The framework, termed Generative Quantum AI (GenQAI), involved a quantum computer simulating a pharmaceutical compound using programming instructions generated by an AI model, which itself was trained on quantum data that was simulated using HPC.
While the vision for GenQAI explores how future industrial simulation workflows might be optimized by training AI models using quantum data derived directly from a quantum computer, the framework currently consists of four main technical steps:
- Simulating quantum data: The process began by simulating quantum data with NVIDIA accelerated computing using NVIDIA CUDA-Q.
- Fine-tuning the AI: This simulated quantum data was used to fine-tune a pre-trained AI model from the open NVIDIA Nemotron family.
- Generating instructions: The AI model then generated quantum circuits, which are the programming instructions required for the quantum simulation.
- Validating accuracy: To validate the results, the circuits were run on Quantinuum’s Helios quantum computer using its InQuanto quantum chemistry platform.
The core novelty of this development lies within the process of the framework itself. In this proof-of-principle experiment, an AI model fine-tuned on simulated quantum data generated circuits that were successfully executed and validated on Quantinuum’s Helios system. Rather than delivering an immediate commercial advantage, this achievement establishes a credible, verifiable baseline for how HPC, AI, and quantum computing can function in tandem.
The Case Study
The validation of the framework represents an early step toward the goal of developing scalable architectures for the pharmaceutical industry.
With a shared view toward eventually scaling the framework for pharmaceutical R&D applications, the researchers simulated a pharmaceutical compound: imipramine. This anti-depressant was chosen because it serves as a model compound for drug degradation and shelf-life studies, which are standard components of the pharmaceutical R&D lifecycle.
Developing hybrid infrastructure that enterprises may adopt requires a deep, coordinated effort among domain experts. As such, this successful test highlights the value of combining the strengths of a quantum computing hardware and software leader (Quantinuum), with a hybrid-quantum classical platform (NVIDIA), and a leading enterprise end-user to build and test future computing capabilities for industrial chemistry.
Scaling the Framework
Although demonstrated on a pharmaceutical compound, the architecture could eventually inform similar molecular-simulation workflows in sectors such as energy, agriculture, advanced materials, and electronics. At this stage, it provides a reference for further testing and development.
Engage Further
Access the paper here to explore the full technical details of this demonstration and contact our team to learn more about joining Quantinuum’s enterprise partner network.
Quantinuum is pleased to announce that applications are now open for the Quantinuum SG Grand Challenge 2026, a global innovation challenge designed to bring together researchers, developers, scientists and innovators to explore practical applications of quantum computing.
Organized by Quantinuum and supported by Singapore's National Quantum Office and Aqora, the three-month program aims to foster collaboration across academia, industry and the quantum developer community while supporting the continued growth of Singapore's quantum ecosystem.
A Platform for Quantum Computing Innovation
Participants will work in teams to develop solutions across a range of challenge areas, including chemistry and molecular simulation, optimization, AI for quantum systems, quantum error correction, condensed matter and materials science, and open innovation. Throughout the program, participants will have access to mentoring, technical enablement and Quantinuum quantum computing resources.
Singapore Grand Finale
Selected finalist teams will be invited to present their work at the Grand Finale hosted in Singapore before representatives from academia, and industry. The event will celebrate innovative applications of quantum computing while providing an opportunity for participants to engage with Singapore's growing quantum community.
Join the Challenge
The Quantinuum SG Grand Challenge welcomes participants from around the world. Whether you are an experienced quantum researcher or beginning your quantum computing journey, the program offers an opportunity to collaborate, learn and contribute to the development of practical quantum applications.
Applications are now open. Spaces are limited and subject to review and approval.
- Researchers from Quantinuum, Caltech, the University of Chicago, and Harvard created a rare topologically ordered state of matter on Quantinuum's System Model H2 and used it to perform protected universal quantum gates with non-Abelian anyons.
- The work explores an alternative approach to fault tolerance by using topological properties to protect quantum information. This could reduce the need for magic state distillation, which can (in some circumstances) be resource-intensive.
- Quantinuum continues to show leadership in fault tolerance, with successful demonstrations spanning world record error rates to exotic approaches like topological computing
Quantum computing is all about putting the exotic properties of physics to work. Qubits can exist in two states at once, like the famous cat that is both alive and dead. Qubits can also be entangled, where the state of one will instantaneously affect the state of another - even when they have no way to “talk” to each other. Qubits can even be teleported, moving a quantum state from one place to another without physically moving it through space.
These features give quantum computing its power. But the ‘spooky’ nature of quantum computing doesn’t stop there: our quantum computers are potent enough to make exotic states of matter out of our qubits, and to perform calculations that would warp the mind of more traditional thinkers.
A new approach
In a recent paper published in Nature, researchers at Quantinuum teamed up with Caltech, the University of Chicago, and Harvard to create a rare ‘topologically ordered’ state of matter from our qubits.
When the qubits become ‘topologically ordered’, they become more than individual particles, now ‘related’ to each other in a specific way. This is like how hydrogen and oxygen act as individual gas particles alone, but you can put them together in a certain way so that they become water, a liquid, and an entirely different creature.
When the qubits become topologically ordered, the quantum information that they carried individually gets spread out over the whole system, which acts as a sort of protection from noise. This is like how a net makes a stronger barrier than a bunch of un-knotted ropes.
Once the researchers had topologically ordered qubits, they used the exotic particles that resulted (called non-Abelian anyons) to compute, performing error-protected gates and measurements.
To perform gates, the researchers 'braided' the anyons, which is like changing the shape of the “net”. This is something like the children’s game ‘cats cradle’. Through a sequence of changes to the “net”, the quantum computer can perform full calculations, one day helping scientists to understand the secrets hidden in the world around us.
Why go to such trouble? Well, for the love of discovery of course - but the team had an additional, specific motivation. One of the biggest challenges in building practical quantum computers is protecting them from errors while still being able to perform every operation needed for computation (this is referred to as universality).
This work takes a fresh approach to this challenge. Unlike traditional quantum error correction, the special properties of topological matter enable a universal set of fault tolerant gates without relying on expensive magic state distillation.
Why this matters
Quantum error correction is essential for large-scale quantum computing. While it protects fragile quantum information from noise by turning delicate physical qubits into robust logical qubits, it also introduces a significant constraint: not every quantum gate can be performed directly on logical qubits.
For decades, the standard solution has been to supplement error-corrected operations with magic states. These specially prepared quantum resources enable universal computation but can come at a steep cost - in many estimates of future fault-tolerant quantum computers, magic state preparation dominates both the physical qubit count and the runtime of useful algorithms.
Reducing this overhead has therefore become an important goal in quantum computing. This new approach may significantly reduce the cost by enabling the ‘topological preparation’ of magic states, eliding expensive protocols like distillation. If universal computation can be performed without large-scale magic state distillation, quantum computers could require significantly fewer physical qubits and spend much less time generating computational resources before running useful algorithms.
We will never stop exploring
While there is still considerable work ahead to understand the practical implementation and scalability of these ideas, this result expands the landscape of what's possible in quantum fault tolerance.
Of course, this impressive demonstration describes just one approach we are taking to fault tolerance at scale. We will continue to push forward with topological computing alongside more traditional approaches to quantum error correction, as well as exploring everything we can imagine in between. We are looking at a number of ways to reduce the resource cost of magic states in particular, and are making strides in multiple dimensions. With machines that are both flexible and accurate enough to do it all, who can resist?