Developing “Killer Apps” for Quantum Computing
Logistics, Supply Chain and Routing
By Kevin Jackson for Quantinuum
The world is a lot smaller than it was in the previous century – or even in the previous decade.
Customers are now accustomed to a wide variety of products that can be delivered from distributors all over the globe. While this is a great opportunity for suppliers, it also presents a challenge in the form of supply chain, logistics, routing, and optimization.
How can distribution companies continue to serve the needs of their customers in the most efficient and effective way possible? This may seem like a simple question, but it becomes a complex computational problem when trying to account for all the variables that can occur within a distribution network.
What’s more, classical computers simply cannot adequately perform this optimization calculation in real-world scenarios. Because of the number of variables, the math just runs too slow.
That said, new work in quantum computing has shown promise in applications within the optimization field. To that end, we interviewed Quantinuum’s Megan Kohagen and Dr. Mattia Fiorentini to better understand how quantum computing could to optimized logistics and supply chains.
Kohagen and Fiorentini are participating in a panel about quantum computing at Manifest: The Future of Logistics conference this week in Las Vegas, Nevada.
Beyond classical computing
When it comes to optimization it is all about maximizing or minimizing an objective. A good example is a company that delivers goods and products but owns a limited number of trucks. To improve efficiency and minimize costs, the company needs to maximize the number of objects its trucks carry and identify the shortest routes between deliveries.
“You have all these constraints, you have your objective, and you’ve got to make decisions,” said Kohagen, an optimization researcher. “The decisions end up being things like how many goods you are going to send between your distribution centers and your stores? Each of these optimization problems, even if you consider them separately, are hard problems. The technical term is that they’re (non-deterministic polynomial)-hard because you’re dealing with discrete things. For example, I can’t send half a T-shirt to my customer. I can only operate with whole integers.”
Fiorentini expands on this: “In logistics, we cannot leave anyone behind. If we need to deliver medicine, we cannot decide ‘the villages with less than 1,000 people – we don’t supply them. There are too many, and not enough people live there’. That’s not an option in today’s world.”
Today’s computers struggle to solve these NP-hard optimization problems because of the number of ever-changing variables. Consider the much-studied Traveling Salesperson Problem, which is often used to illustrate the complexity of managing logistics, routing, and supply chains.
This is a theoretical problem where a machine is tasked with finding the shortest route between an identified list of cities that a “salesperson” must visit before returning to the point of origin. This problem is simple enough with only a few cities, but it becomes exponentially harder as more locations are added, and other factors such as multiple salespeople, weather conditions, and unforeseen events arise.
Classical computers can solve this theoretical problem for a single salesperson traveling to thousands of cities. But this scenario is not realistic, and this is where classical computers begin to struggle.
“The Traveling Salesperson Problem is not very representative of what happens in the real world,” Kohagen said. “For example, with online ordering so prevalent, a retailer has orders coming in constantly. They must determine how to efficiently retrieve those items from the warehouse, pack them into the trucks, and then transport them to the customers.”
Today, the reality of an extended supply chain or distribution network is beyond what the best classical computer can solve. Quantum computers harness unique properties of quantum physics that enable them to examine all possible answers simultaneously and then concentrate the probable output of the computation onto the best option.
“Classical is a great technology, but it doesn’t cut it here,” said Fiorentini, who develops and tests quantum algorithms for optimization. “Quantum is the best alternative to classical computing that we have.“
The quantum computing opportunity
Optimization problems have long been viewed as “killer applications” for quantum computing and research conducted by Fiorentini, Kohagen and others has begun to prove that.
Fiorentini believes it is time for decision makers to explore and invest in quantum-enabled solutions for optimization problems. “There are two decisions here for decision makers,” he said. “We either give up on the problem and say, ‘we’ll just do the best we can with a classical solution, or we start allocating a budget for really developing quantum technology.”
Quantum computing is expanding rapidly and is poised to disrupt markets such as optimization. A similar situation is the power sector, which is experiencing major disruptions due to innovations in renewable energy resources, energy storage, and regulatory reform.
Every technology has a tipping point, and all signs point to a current trend in quantum computing moving rapidly to real-world applications in optimization.
“There are a lot of algorithms being developed for optimization right now,” said Kohagen. “If you really want to advance your business with quantum methods for logistics or supply chain, this is the moment to start. Decision makers must act quickly. Those that seize the opportunity before others will have a major advantage over those who lag.”
“As quantum computers continue to scale in computational power, they’ll be able to handle increasingly complex calculations to deliver more robust and optimized supply chain solutions,” said Tony Uttley, President and COO of Quantinuum.
“We’re excited by the acceleration of our System Model H1 technologies, Powered by Honeywell. Measured in terms of qubit number as well as quantum volume, we’re meeting our commitment to increase performance by a factor of 10X each year,” he said. “Alongside other revolutionary advances such as real-time error correction, we look forward to supporting the commercialization of quantum applications that will change the way logistical challenges are met. In fact, within the coming few months we’ll be sharing more exciting news regarding our latest technological achievements.”
Want to learn about our work to develop quantum-enabled optimization solutions for companies? Contact our experts
About Quantinuum
Quantinuum, the world’s largest integrated quantum company, pioneers powerful quantum computers and advanced software solutions. Quantinuum’s technology drives breakthroughs in materials discovery, cybersecurity, and next-gen quantum AI. With over 500 employees, including 370+ scientists and engineers, Quantinuum leads the quantum computing revolution across continents.
Thirty participants gathered at Newnham College, Cambridge, for an intensive five-day programme exploring how quantum computers can be used to model chemical systems.
By: Duncan Gowland, Senior Advanced R&D Scientist at Quantinuum
For 30 researchers who gathered at Newnham College, Cambridge this September, that question shaped an intensive five-day programme.
Quantinuum’s first InQuanto Summer School, supported by the UK’s National Quantum Computing Centre (NQCC), combined lectures, hands-on workshops, and mini-projects to help participants connect fundamental concepts with practical research. By the end of the week, participants were applying those ideas to problems ranging from molecular electronic structure to quantum state-preparation circuits.
Applying quantum computing to chemistry can be challenging because it draws on expertise from a broad range of areas, including electronic structure theory, quantum algorithms, software, hardware, noise modelling, and resource estimation. Researchers often enter the field with deep knowledge of one or two of these areas but less familiarity with the others.
A key objective of the course was to help researchers from computational chemistry and quantum computing build stronger foundations, develop a shared language, and deepen their understanding of adjacent disciplines.
For researchers beginning work at this intersection, that shared understanding can make it easier to identify where to start, which assumptions to challenge, and when to seek expertise from another discipline.
Bringing Theory and Practice Together
The programme began with lectures on the foundations of quantum computing, followed by pen-and-paper and computational exercises in the afternoon. On Day 2, lectures and workshops introduced the electronic structure problem: how quantum chemists describe the behaviour of electrons in molecules.
Students then brought these two foundations together by studying fermion-to-qubit mappings, which translate chemistry problems into a form that quantum computers can process, before moving on to the measurement of chemistry observables and the construction of quantum algorithms.
Learners were given free access to InQuanto, Quantinuum’s quantum chemistry software platform designed to accelerate research in fields such as chemistry and condensed matter physics using quantum computers. InQuanto supported the lectures as a broad, well-documented, and thoroughly tested platform that enabled students to explore and reinforce complex concepts through hands-on experience.
Later in the week, attention shifted to state-of-the-art considerations: how to build useful chemical models, make the best use of current quantum devices, and think about how quantum algorithms for chemistry might develop over the next five to ten years.
The students, who travelled from around the world to Cambridge, brought a remarkable range of backgrounds and experience. The material was pitched at roughly first-year doctoral level, for participants with at least a year of experience in one core area and some Python skills. Even with this experience, participants benefited from exposure to other disciplines and from the practical expertise of Quantinuum’s quantum chemistry team—which brings years of experience working with industrial including BMW Group, TotalEnergies, NVIDIA, and Pfizer.
Throughout the week, participants were highly engaged in lectures and brought a thoughtful, collaborative approach to the workshop exercises. Discussions continued throughout the week, from coffee breaks to lunches and dinners, creating valuable opportunities to exchange ideas and experiences.
A particular highlight was the mini-project work. In just a day and a half, participants tackled a wide range of problems and produced impressive prototype solutions. The projects concluded with a poster-style session, where the quality of discussion was exceptional. Examples included state-preparation programmes using mid-circuit measurement in Guppy; investigations of active-space selection and quantum-selected configuration interaction (QSCI) for the chromium dimer; and the use of the atomic valence active space (AVAS) approach to identify active spaces and perform resource estimation for myoglobin.
One participant reimplemented their research on efficient state-preparation circuits based on orbital entanglement in InQuanto and compared the performance of those circuits with the platform’s efficient ansatz methods on the Helios emulator. It was rewarding to see participants apply these tools to their own research challenges and explore new approaches to quantum chemistry.
With Support from the UK’s National Quantum Computing Centre
This rewarding week was made possible through the support of the UK’s National Quantum Computing Centre, whose partnership helped bring the programme to life, and by the contributions of colleagues across Quantinuum. The teaching team brought together experts from our quantum chemistry, compiler, and error-correction teams, who developed the course materials, delivered lectures, and led the workshops.
Above all, the programme demonstrated the value of bringing researchers together around a shared foundation, practical tools, and opportunities to learn from one another. We look forward to seeing how participants build on these ideas in their future research.
Interested in future training opportunities, workshops, and community events from Quantinuum? Join QNET to stay connected with the latest updates, resources, and opportunities to engage with the quantum computing community.
For years, the quantum landscape has been crowded with headline hype, speculative roadmaps, and vanity qubit counts.
While that noise hasn't completely disappeared, Quantum World Congress 2026 proved that the market's tolerance for hype is rapidly wearing thin. While benchmark simulations and roadmap announcements still generate headlines, the real conversation on the ground has shifted toward a far more demanding question: who is actually delivering useful execution today and making meaningful progress toward fault-tolerant quantum computing?
At Quantinuum, our stance has never wavered. Progress is measured by delivering integrated systems that perform useful computation reliably on real hardware and in live enterprise environments. Prove what you can do and publish the results.
What was most encouraging this year at Quantum World Congress was seeing much of the industry increasingly align around that view, with the conversation converging around several priorities in particular.
1. Fault tolerance proven on real hardware is the only credible path to scale
The industry is converging around a shared reality: useful quantum computing will be defined by fault tolerance.
But fault tolerance is not a single metric, a logical-qubit count, or a standalone error-correction demonstration. It requires a complete end-to-end architecture that can detect, correct, and manage errors across every layer of computation, from logical operations to resource-state preparation, and execution of useful algorithms on live hardware.
That is why context matters when evaluating industry announcements.
Demonstrating more logical qubits is not the same as demonstrating fault tolerance. Demonstrating real-time decoding in a simulation is not the same as demonstrating real-time quantum error correction on real hardware. Logical qubits, decoders, syndrome extraction, and resource-state preparation are all necessary ingredients. But proving an individual ingredient in isolation, particularly through simulations or benchmark environments, is fundamentally different from proving that a complete fault-tolerant architecture works on a live quantum computer.
The industry should not confuse progress on individual building blocks with proof of a scalable fault-tolerant system. The real test is whether all these capabilities work together to improve computational performance beyond the physical layer and in a way that can scale.
This is exactly what Quantinuum's Helix architecture is designed to do.
Running on our Helios system, Helix integrates the full stack required for fault-tolerant quantum computing and has already delivered world-class results on live commercial hardware. Helios achieves physical two-qubit gate error rates of 8×10⁻⁴, while Helix has demonstrated a logical compute error rate of 2.8×10⁻⁴, representing a 4.28× improvement over the physical Clifford gate error rate without post-selection, meaning no cherry-picked results.
Just as importantly, Helix improves efficiency as well as reliability. Through adaptive syndrome extraction, it reduces physical gate requirements by 33% and wall-clock execution time by 23%. Today, the architecture is already supporting full computations using 64 error-detected logical qubits with better-than-physical performance and a highly efficient 1:1.5 encoding rate.
These results matter because they demonstrate more than isolated milestones. They show that a scalable fault-tolerant architecture is operating on real hardware today and delivering measurable improvements in computational reliability. As physical systems grow, Helix provides the framework that enables additional scale to translate into increasingly reliable computation.
The path to fault tolerance will continue to evolve. New codes, encoding approaches, and implementation techniques will emerge over time. What remains constant is the need for an architecture capable of orchestrating those innovations into a practical, scalable system. We believe Helix is well positioned to serve as that architecture.
2. The industry must measure performance with useful, standardized metrics
Customers cannot make informed buying decisions if every vendor continues to grade their own homework. Standardized benchmarks are critical because they shift the conversation from theoretical promises to actual, measurable usefulness.
While earlier benchmarks like Quantum Volume were helpful for NISQ-era systems, they don’t keep pace as fault-tolerant systems scale beyond classical simulation limits. That is why Quantinuum is helping drive industry alignment around QUOPS, developed by Sandia National Laboratories with input from NVIDIA and Quantinuum.
QUOPS measures true computational capability by evaluating both computational Size (QUOPS) and Speed (QUOPS/sec). It’s the difference between rating an engine by theoretical horsepower versus measuring how fast and far a vehicle can drive on an actual track.
Most importantly, QUOPS evaluates the capability delivered by the complete computing stack. As the industry moves toward fault-tolerant systems, useful benchmarks must measure the performance of the entire architecture rather than individual subsystems. They must remain transparent as workloads scale, allowing enterprises to clearly evaluate the real-world utility of a system for their specific problem sets.
3. The industrial manufacturing race is on
Proving a fault-tolerant concept on a laboratory bench is only the first step. The transition to utility-scale computing is fundamentally an engineering, supply chain, and manufacturing race.
Our roadmap clearly defines how we scale from a single chip with a 2D-grid layout to larger multi-chip packages. Rather than reinventing the wheel, we are leveraging proven semiconductor manufacturing techniques that built the modern microelectronics industry. We have backed this architecture with a world-class industrial ecosystem, partnering with commercial foundries and component leaders.
The companies that win the next phase of quantum computing will not simply invent breakthrough technologies. They will demonstrate the ability to manufacture, deploy, and scale them reliably.
4. Growing the ecosystem requires a powerful developer platform built for the fault-tolerant era
A high-performing QPU is only part of the equation. You also need the software layer required to run it. For quantum to succeed, it must integrate into the workflows developers and enterprise researchers are already using today.
Nexus is our developer platform designed to be the purpose-built enterprise integration layer, designed from the ground up to squeeze maximum power and accuracy out of Quantinuum’s architectures. Nexus provides seamless interoperability across native Guppy, NVIDIA CUDA-Q, and Microsoft Q#, directly connecting quantum hardware to classical AI and HPC environments.
This is not an experimental platform. It is already supporting meaningful commercial adoption today.
Adopted by more than 200 organizations, representing approximately 45% growth, and used by more than 1,000 active developers, Nexus has seen annual job submissions increase 10x when comparing August 2024-August 2025 with August 2025-August 2026.
As quantum computing enters the fault-tolerant era, the winning platform will be the one that makes advanced quantum capabilities accessible within the workflows enterprises already depend on.
5. Real progress is measured in live production deployments and real-world research
The future of high-performance computing isn't quantum versus AI or HPC. It is all three working together as a unified compute stack.
But we believe the true test of market leadership isn't a self-funded trial or a desktop simulation that claims hybrid integration. It is putting live hardware into mission-critical operational environments to solve real enterprise problems and advance meaningful science.
That is why we are focused on embedding our quantum systems directly into global computing infrastructure. Through our partnership with Oracle, we expect to bring commercial-scale quantum computing directly into an Oracle Cloud Infrastructure AI data center, with the goal of letting enterprise customers run quantum applications within their existing cloud footprint.
Similarly, our deep, multi-year collaboration with NVIDIA continues to advance the frontiers of hybrid compute: from co-founding the NVAQC center in Boston to physically integrating NVIDIA GPUs into our Helios hardware for real-time error correction, to running live workflows with Pfizer to help accelerate pharmaceutical discovery.
Ultimately, as we scale these capabilities from the system level to the enterprise, we believe quantum computing can serve as the crucial engine to unlock far greater value from classical AI. By integrating QPUs alongside GPUs and supercomputers, we are working to move beyond the limitations of classical compute alone.
This hybrid approach enables enterprises to generate higher-quality quantum training data, build more powerful models, and tackle complex chemistry and materials challenges that remain beyond the reach of classical AI by itself.
Looking Ahead
Quantum World Congress 2026 proved that the market is finally asking the right questions:
- How do we achieve true fault tolerance at scale?
- How do we measure objective computational capability?
- How do we deploy quantum systems to solve real-world enterprise problems?
The conversation is shifting from theoretical possibility to demonstrated capability. From isolated milestones to integrated systems. From simulations to real hardware. That is where meaningful progress happens. And that is where Quantinuum intends to continue to lead.
Forward-Looking Statements:
This blog post contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995, including statements about expected product capabilities, technology development timelines, planned partnerships and deployments, and anticipated market trends, and expected business metrics and growth rates. These statements are based on current expectations and assumptions and are subject to risks and uncertainties that could cause actual results to differ materially, including risks related to technology development, competitive dynamics, customer adoption, and partnership execution. Forward-looking statements speak only as of the date made, and Quantinuum undertakes no obligation to update them. For a discussion of factors that could affect outcomes, please refer to Quantinuum's public filings.
For enterprise and public sector executives evaluating quantum computing investment
Quantum computing is now a strategic priority for many organizations. It's on track to help solve some of the world's biggest challenges, from drug discovery, to materials science, to optimization problems – all at a scale classical computers simply can't reach. For executives responsible for R&D, technology strategy, or innovation investment, the question is no longer whether quantum computing matters. It's how to approach it wisely.
That's a harder question than it sounds. The quantum computing market is crowded, technical, and moving fast, and most of the guidance available is written for physicists, not for the executives who actually have to make the investment decision. Vendor claims are difficult to compare, pilot programs are easy to get wrong, and the gap between "quantum is exciting" and "quantum is worth investing in this year" isn't always well explained.
Our new guide, A Strategic Guide to Selecting the Right Quantum Computing Solution, is built to close that gap.
What's Inside
The guide is designed to give business and technology leaders a clear, practical path through four essential questions:
- Why quantum computing matters now, and why the window for early strategic advantage is open today
- How to evaluate vendors objectively, using a structured framework rather than marketing claims
- How to design an effective pilot, so early investment produces real, usable evidence
- How to take your first steps with confidence, whether you're just starting to explore or ready to scale
It also includes a glossary of key terms, so readers new to the field aren't left decoding jargon before they can evaluate a single vendor.
Who Should Read It
The guide is written for CTOs, CIOs, CISOs, R&D leaders, and program directors across enterprise and public sector organizations, at any stage of quantum familiarity. Whether your organization hasn't yet started exploring quantum computing, or you already have a program underway and are looking to sharpen your evaluation process, the framework inside is designed to apply.
How to Use It
The evaluation framework at the core of the guide isn't specific to any one vendor; it's designed to be applied to any quantum computing solution you're considering, so you can make an apples-to-apples comparison based on your organization's actual needs. The guide also walks through how Quantinuum maps to that same framework, and what it looks like to work with Quantinuum as a co-development partner, should you want a concrete reference point alongside the general framework.
Start With Confidence, Not Guesswork
Quantum computing is a strategic decision, not just a technical one. The organizations that approach it with a clear framework, rather than reacting to the noise, will be the ones positioned to capture real value as the technology matures.