How we equip our users to unlock the full potential of H-Series Quantum Computers

July 12, 2023

In a series of recent technical papers, Quantinuum researchers demonstrated the world-leading capabilities of the latest H-Series quantum computers, and the features and tools that make these accessible to our global customers and users.

A computer network with different symbolsDescription automatically generated

Our teams used the H-Series quantum computers to directly measure and control non-abelian topological states of matter [1] for the first time, explore new ways to solve combinatorial optimization problems more efficiently [2], simulate molecular systems using logical qubits with error detection [3], probe critical states of matter [4], as well as exhaustively benchmark our very latest system [5].

Part of what makes such rapid technical and scientific progress possible is the effort our teams continually make to develop and improve workflow tools, helping our users to achieve successful results. In this blog post, we will explore the capabilities of three new tools in some detail, discuss their significance, and highlight their impact in recent quantum computing research.

Leakage Detection Gadget in pyTKET

“Leakage” is a quantum error process where a qubit ends up in a state outside the computational subspace and can significantly impact quantum computations. To address this issue, Quantinuum has developed a leakage detection gadget in pyTKET, a python module for interfacing with TKET, our quantum computing toolkit and optimizing compiler. This gadget, presented at the 2022 IEEE International Conference [6], acts as an error detection technique: it detects and excludes results affected by leakage, minimizing its impact on computations. It is also a valuable tool for measuring single-qubit and two-qubit spontaneous emission rates. H-Series users can access this open-source gadget through pyTKET, and an example notebook is available on the pyTKET GitHub repository. 

Mid-Circuit Measurement and Qubit Reuse (MCMR) Package

The MCMR package, built as a pyTKET compiler pass, is designed to reduce the number of qubits required for executing many types of quantum algorithms, expanding the scope of what is possible on the current-generation H-Series quantum computers. 

As an example, in a recent paper [4], Quantinuum researchers applied this tool to simulate the transverse-field Ising model and used only 20 qubits to simulate a much larger 128 site system (there is more detail below on this work). By measuring qubits early in the circuit, resetting them, and reusing them elsewhere, the package ingests a raw circuit and outputs an optimized circuit that requires fewer quantum resources. Previously, a scientific paper [7] and blog post on MCMR were published highlighting its benefits and applications. H-Series customers can download this package via the Quantinuum user portal.

Quantinuum H2-1 Emulator Release

To enable efficient use of Quantinuum’s 2nd generation processor, the System Model H2, Quantinuum has released the H2-1 emulator to give users greater flexibility with noise-informed state vector emulation. This emulator uses the NVIDIA's cuQuantum SDK to accelerate quantum computing simulation workflows, nearly approaching the limit of full state emulation on conventional classical hardware. The emulator is a faithful representation of the QPU it emulates. This is accomplished by not only using realistic noise models and noise parameters, but also by sharing the same software stack between the QPU and the emulator up until the job is either routed to the QPU or the classical computing processors. Most notable is that the emulator and the QPU use the same compiler allowing subtle and time-dependent errors to be appropriately represented. The H2-1 emulator was initially released as a beta product alongside the System Model H2 quantum computer at launch. It runs on a GPU backend and an upgraded global framework now offering features such as job chunking, incremental resource distribution, mid-execution job cancellation, and partial result return. Detailed information about the emulator can be found in the H2 emulator product datasheet on the Quantinuum website. H-Series customers with an H2 subscription can access the H2-1 emulator via an API or the Microsoft Azure platform.

Enabling Recent Works

Quantinuum's new enabling tools have already demonstrated their efficacy and value in recent quantum computing research, playing a vital role in advancing the field and achieving groundbreaking results. Let's expand on some notable recent examples.

All works presented here benefited from having access to our H-Series emulators; of these two significant demonstrations were the “Creation of Non-Abelian Topological Order and Anyons on a Trapped-Ion Processor” [1] and “Demonstration of improved 1-layer QAOA with Instantaneous Quantum Polynomial” [2]. These demonstrations involved extensive testing, debugging, and experiment design, for which the versatility of the H2-1 emulator proved invaluable, providing initial performance benchmarks in a realistic noisy environment. Researchers relied on the emulator's results to gauge algorithmic performance and make necessary adjustments. By leveraging the emulator's capabilities, researchers were able to accelerate their progress.

The MCMR package was extensively used in benchmarking the System Model H2 quantum computer’s world-leading capabilities [5]. Two application-level benchmarks performed in this work, approximating the solution to a MaxCut combinatorics problem using the quantum approximate optimization algorithm (QAOA) and accurately simulating a quantum dynamics model using a holographic quantum dynamics (HoloQUADS) algorithm, would have been too large to encode on H2's 32 qubits without the MCMR package. Further illustrating the overall value of these tools, in the HoloQUADS benchmark, there is a "bond qubit" that is particularly susceptible to errors due to leakage. The leakage detection gadget was used on this "bond qubit" at the end of the circuit, and any shots with a detected leakage error were discarded. The leakage detection gadget was also used to obtain the rate of leakage error per single-qubit and two-qubit gates, two component-level benchmarks.

In another scientific work [4], the MCMR compilation tool proved instrumental to simulating a transverse-field Ising model on 128 sites, using 20 qubits. With the MCMR package and by leveraging a state-of-the-art classical tensor-network ansatz expressed as a quantum circuit, the Quantinuum team was able to express the highly entangled ground state of the critical Ising model. The team showed that with H1-1's 20 qubits, the properties of this state could be measured on a 128-site system with very high fidelity, enabling a quantitatively accurate extraction of some critical properties of the model.

Key Takeaways

At Quantinuum, we are entirely devoted to producing a quantum hardware, middleware and software stack that leads the world on the most important benchmarks and includes features and tools that provide breakthrough benefit to our growing base of users.  In today's NISQ hardware, "benefit" usually takes the form of getting the most performance out of today’s hardware, continually pushing what is considered to be possible. In this blog we describe two examples: error detection and discard using the “leakage detection gadget” and an automated method for circuit optimization for qubit reuse. “Benefit” can also take other forms, such as productivity. Our emulator brings many benefits to our users, but one that resonates the most is productivity. Being a faithful representation of our QPU performance, the emulator is an accessible tool which users have at their disposal to develop and test new, innovative algorithms. The tools and features Quantinuum releases are driven by users’ feedback; whether you are new to H-Series or a seasoned user, please reach-out and let us know how we can help bring benefit to your research and use case.

Footnotes:

[1] Mohsin Iqbal et al., Creation of Non-Abelian Topological Order and Anyons on a Trapped-Ion Processor (2023), arXiv:2305.03766 [quant-ph]

[2] Sebastian Leontica and David Amaro, Exploring the neighborhood of 1-layer QAOA with Instantaneous Quantum Polynomial circuits (2022), arXiv:2210.05526 [quant-ph]

[3] Kentaro Yamamoto, Samuel Duffield, Yuta Kikuchi, and David Muñoz Ramo, Demonstrating Bayesian Quantum Phase Estimation with Quantum Error Detection (2023), arXiv:2306.16608 [quant-ph]

[4] Reza Haghshenas, et al., Probing critical states of matter on a digital quantum computer (2023),
arXiv:2305.01650 [quant-ph]

[5] S. A. Moses, et al., A Race Track Trapped-Ion Quantum Processor (2023), arXiv:2305.03828 [quant-ph]

[6] K. Mayer, Mitigating qubit leakage errors in quantum circuits with gadgets and post-selection, 2022 IEEE International Conference on Quantum Computing and Engineering (QCE), Broomfield, CO, USA, (2022), pp. 809-809, doi: 10.1109/QCE53715.2022.00126.

[7] Matthew DeCross, Eli Chertkov, Megan Kohagen, and Michael Foss-Feig, Qubit-reuse compilation with mid-circuit measurement and reset (2022), arXiv:2210.08039 [quant-ph]

About Quantinuum

Quantinuum, the world’s largest integrated quantum company, pioneers powerful quantum computers and advanced software solutions. Quantinuum’s technology drives breakthroughs in materials discovery, cybersecurity, and next-gen quantum AI. With over 500 employees, including 370+ scientists and engineers, Quantinuum leads the quantum computing revolution across continents. 

Blog
August 28, 2025
Quantum Computing Joins the Next Frontier in Genomics
  • The Sanger Institute illustrates the value of quantum computing to genomics research
  • Quantinuum supports developments in a field that promises to deliver a profound and positive societal impact

Twenty-five years ago, scientists accomplished a task likened to a biological moonshot: the sequencing of the entire human genome.

The Human Genome Project revealed a complete human blueprint comprising around 3 billion base pairs, the chemical building blocks of DNA. It led to breakthrough medical treatments, scientific discoveries, and a new understanding of the biological functions of our body.

Thanks to technological advances in the quarter-century since, what took 13 years and cost $2.7 billion then can now be done in under 12 minutes for a few hundred dollars. Improved instruments such as next-generation sequencers and a better understanding of the human genome – including the availability of a “reference genome” – have aided progress, alongside enormous advances in algorithms and computing power.

But even today, some genomic challenges remain so complex that they stretch beyond the capabilities of the most powerful classical computers operating in isolation. This has sparked a bold search for new computational paradigms, and in particular, quantum computing.

Quantum Challenge: Accepted

The Wellcome Leap Quantum for Bio (Q4Bio) challenge is pioneering this new frontier. The program funds research to develop quantum algorithms that can overcome current computational bottlenecks. It aims to test the classical boundaries of computational genetics in the next 3-5 years.

One consortium – led by the University of Oxford and supported by prestigious partners including the Wellcome Sanger Institute, the Universities of Cambridge, Melbourne, and Kyiv Academic University – is taking a leading role.

“The overall goal of the team’s project is to perform a range of genomic processing tasks for the most complex and variable genomes and sequences – a task that can go beyond the capabilities of current classical computers” – Wellcome Sanger Institute press release, July 2025
Selecting Quantinuum

Earlier this year, the Sanger Institute selected Quantinuum as a technology partner in their bid to succeed in the Q4Bio challenge.

Our flagship quantum computer, System H2, has for many years led the field of commercially available systems for qubit fidelity and consistently holds the global record for Quantum Volume, currently benchmarked at 8,388,608 (223).

In this collaboration, the scientific research team can take advantage of Quantinuum’s full stack approach to technology development, including hardware, software, and deep expertise in quantum algorithm development.

“We were honored to be selected by the Sanger Institute to partner in tackling some of the most complex challenges in genomics. By bringing the world’s highest performing quantum computers to this collaboration, we will help the team push the limits of genomics research with quantum algorithms and open new possibilities for health and medical science.” – Rajeeb Hazra, President and CEO of Quantinuum
Quantum for Biology

At the heart of this endeavor, the consortium has announced a bold central mission for the coming year: to encode and process an entire genome using a quantum computer. This achievement would be a potential world-first and provide evidence for quantum computing’s readiness for tackling real-world use cases.

Their chosen genome, the bacteriophage PhiX174, carries symbolic weight, as its sequencing earned Fred Sanger his second Nobel Prize for Chemistry in 1980. Successfully encoding this genome quantum mechanically would represent a significant milestone for both genomics and quantum computing.

Bacteriophage PhiX174, published under a Creative Commons License https://commons.wikimedia.org/wiki/File:Phi_X_174.png

Sooner than many expect, quantum computing may play an essential role in tackling genomic challenges at the very frontier of human health. The Sanger Institute and Quantinuum’s partnership reminds us that we may soon reach an important step forward in human health research – one that could change medicine and computational biology as dramatically as the original Human Genome Project did a quarter-century ago.

“Quantum computational biology has long inspired us at Quantinuum, as it has the potential to transform global health and empower people everywhere to lead longer, healthier, and more dignified lives.” – Ilyas Khan, Founder and Chief Product Officer of Quantinuum

Glossary of terms: Understanding how quantum computing supports complex genomic research


Term Definition
Algorithms
A set of rules or processes for performing calculations or solving computational problems.
Classical Computing Computing technology based on binary information storage (bits represented as 0 or 1).
DNA Sequence The exact order of nucleotides (A, T, C, G) within a DNA molecule.
Genome The complete set of genetic material (DNA) present in an organism.
Graph-based Genome (Sequence Graph) A non-linear network representation of genomic sequences capturing the diversity and relationships among multiple genomes.
High Performance Compute (HPC) Advanced classical computing systems designed for handling computationally intensive tasks, simulations, and data processing.
Pangenome A collection of multiple genome sequences representing genetic diversity within a population or species.
Precision Medicine Tailored medical treatments based on individual genetic, environmental, and lifestyle factors.
Quantinuum The world’s largest quantum computing company, Quantinuum systems lead the world for the rigorous Quantum Volume benchmark and were the first to offer commercial access to highly reliable “Level 2 – resilient” quantum computing.
Quantum Bit (Qubit) Basic unit of quantum information, which unlike classical bits, can exist in multiple states simultaneously (superposition).
Quantum Computing Computing approach using quantum-mechanical phenomena (e.g., superposition, entanglement, interference) for enhanced problem-solving capabilities.
Quantum Pangenomics Interdisciplinary field combining quantum computing with genomics to address computational challenges in analyzing genetic data and pangenomes.
Quantum Volume A specific test of a quantum computer’s performance on complex circuits. The higher the quantum volume the more powerful the system. Quantinuum’s 56-qubit System Model H2 achieved a record quantum volume of 8,388,608 in May 2025.
Quantum Superposition A fundamental quantum phenomenon in which particles can simultaneously exist in multiple states, enabling complex computational tasks.
Sequence Mapping Determining how sequences align or correspond within a larger genomic reference or graph.
Wellcome Leap Quantum for Bio (Q4Bio) Initiative funding research combining quantum computing and biological sciences to address computational challenges.
Wellcome Sanger Institute The Sanger Institute tackles some of the most difficult challenges in genomic research.
partnership
All
Blog
August 26, 2025
IEEE Quantum Week 2025

Every year, The IEEE International Conference on Quantum Computing and Engineering – or IEEE Quantum Week – brings together engineers, scientists, researchers, students, and others to learn about advancements in quantum computing.

This year’s conference from August 31st – September 5th, is being held in Albuquerque, New Mexico, a burgeoning epicenter for quantum technology innovation and the home to our new location that will support ongoing collaborative efforts to advance the photonics technologies critical to furthering our product development.

Throughout IEEE Quantum Week, our quantum experts will be on-site to share insights on upgrades to our hardware, enhancements to our software stack, our path to error correction, and more.

Meet our team at Booth #507 and join the below sessions to discover how Quantinuum is forging the path to fault-tolerant quantum computing with our integrated full-stack.

September 2nd

Quantum Software Workshop
Quantum Software 2.1: Open Problems, New Ideas, and Paths to Scale
1:15 – 2:10pm MDT | Mesilla

We recently shared the details of our new software stack for our next-generation systems, including Helios (launching in 2025). Quantinuum’s Agustín Borgna will deliver a lighting talk to introduce Guppy, our new, open-source programming language based on Python, one of the most popular general-use programming languages for classical computing.

September 3rd

PAN08: Progress and Platforms in the Era of Reliable Quantum Computing
1:00 – 2:30pm MDT | Apache

We are entering the era of reliable quantum computing. Across the industry, quantum hardware and software innovators are enabling this transformation by creating reliable logical qubits and building integrated technology stacks that span the application layer, middleware and hardware. Attendees will hear about current and near-term developments from Microsoft, Quantinuum and Atom Computing. They will also gain insights into challenges and potential solutions from across the ecosystem, learn about Microsoft’s qubit-virtualization system, and get a peek into future developments from Quantinuum and Microsoft.

BOF03: Exploring Distributed Quantum Simulators on Exa-scale HPC Systems
3:00 – 4:30pm MDT | Apache

The core agenda of the session is dedicated to addressing key technical and collaborative challenges in this rapidly evolving field. Discussions will concentrate on innovative algorithm design tailored for HPC environments, the development of sophisticated hybrid frameworks that seamlessly combine classical and quantum computational resources, and the crucial task of establishing robust performance benchmarks on large-scale CPU/GPU HPC infrastructures.

September 4th

PAN11: Real-time Quantum Error Correction: Achievements and Challenges
1:00 – 2:30pm MDT | La Cienega

This panel will explore the current state of real-time quantum error correction, identifying key challenges and opportunities as we move toward large-scale, fault-tolerant systems. Real-time decoding is a multi-layered challenge involving algorithms, software, compilation, and computational hardware that must work in tandem to meet the speed, accuracy, and scalability demands of FTQC. We will examine how these challenges manifest for multi-logical qubit operations, and discuss steps needed to extend the decoding infrastructure from intermediate-scale systems to full-scale quantum processors.

September 5th

Keynote by NVIDIA
8:00 – 9:30am MDT | Kiva Auditorium

During his keynote talk, NVIDIA’s Head of Quantum Computing Product, Sam Stanwyck, will detail our partnership to fast-track commercially scalable quantum supercomputers. Discover how Quantinuum and NVIDIA are pushing the boundaries to deliver on the power of hybrid quantum and classical compute – from integrating NVIDIA’s CUDA-Q Platform with access to Quantinuum’s industry-leading hardware to the recently announced NVIDIA Quantum Research Center (NVAQC).

Featured Research at the IEEE Poster Session:

Visible Photonic Component Development for Trapped-Ion Quantum Computing
September 2nd from 6:30 - 8:00pm MDT | September 3rd from 9:30 - 10:00am MDT | September 4th from 11:30 - 12:30pm MDT
Authors: Elliot Lehman, Molly Krogstad, Molly P. Andersen, Sara Cambell, Kirk Cook, Bryan DeBono, Christopher Ertsgaard, Azure Hansen, Duc Nguyen, Adam Ollanik, Daniel Ouellette, Michael Plascak, Justin T. Schultz, Johanna Zultak, Nicholas Boynton, Christopher DeRose,Michael Gehl, and Nicholas Karl

Scaling Up Trapped-Ion Quantum Processors with Integrated Photonics
September 2nd from 6:30 - 8:00pm MDT and 2:30 - 3:00pm MDT | September 4th from 9:30 - 10:00am MDT

Authors: Molly Andersen, Bryan DeBono, Sara Campbell, Kirk Cook, David Gaudiosi, Christopher Ertsgaard, Azure Hansen, Todd Klein, Molly Krogstad, Elliot Lehman, Gregory MacCabe, Duc Nguyen, Nhung Nguyen, Adam Ollanik, Daniel Ouellette, Brendan Paver, Michael Plascak, Justin Schultz and Johanna Zultak

Research Collaborations with the Local Ecosystem

In a partnership that is part of a long-standing relationship with Los Alamos National Laboratory, we have been working on new methods to make quantum computing operations more efficient, and ultimately, scalable.

Learn more in our Research Paper: Classical shadows with symmetries

Our teams collaborated with Sandia National Laboratories demonstrating our leadership in benchmarking. In this paper, we implemented a technique devised by researchers at Sandia to measure errors in mid-circuit measurement and reset. Understanding these errors helps us to reduce them while helping our customers understand what to expect while using our hardware.

Learn more in our Research Paper: Measuring error rates of mid-circuit measurements

events
All
Blog
August 25, 2025
We’re not just catching up to classical computing, we’re evolving from it

From machine learning to quantum physics, tensor networks have been quietly powering the breakthroughs that will reshape our society. Originally developed by the legendary Nobel laureate Roger Penrose, they were first used to tackle esoteric problems in physics that were previously unsolvable.

Today, tensor networks have become indispensable in a huge number of fields, including both classical and quantum computing, where they are used everywhere from quantum error correction (QEC) decoding to quantum machine learning.

In this latest paper, we teamed up with luminaries from the University of British Columbia, California Institute of Technology, University of Jyväskylä, KBR Inc, NASA, Google Quantum AI, NVIDIA, JPMorgan Chase, the University of Sherbrooke, and Terra Quantum AG to provide a comprehensive overview of the use of tensor networks in quantum computing.

Standing on the shoulders of giants

Part of what drives our leadership in quantum computing is our commitment to building the best scientific team in the world. This is precisely why we hired Dr. Reza Haghshenas, one of the world’s leading experts in tensor networks, and a co-author on the paper.

Dr. Haghshenas has been researching tensor networks for over a decade across both academia and industry. Dr. Haghshenas did postdoctoral work under Professor Garnet Chan at Caltech, a leading figure in the use of tensor networks for quantum physics and chemistry.

“Working with Dr. Garnet Chan at Caltech was a formative experience for me”, remarked Dr. Haghshenas. “While there, I contributed to the development of quantum simulation algorithms and advanced classical methods like tensor networks to help interpret and simulate many-body physics.”

Since joining Quantinuum, Dr. Haghshenas has led projects that bring tensor network methods into direct collaboration with experimental hardware teams — exploring quantum magnetism on real quantum devices and helping demonstrate early signs of quantum advantage. He also contributes to widely used simulation tools like QUIMB, helping the broader research community access these methods.

Dr. Haghshenas’ work sits in a broad and vibrant ecosystem exploring novel uses of tensor networks. Collaborations with researchers like Dr. Chan at Caltech, and NVIDIA have brought GPU-accelerated tools to bear on the forefront of applying tensor networks to quantum chemistry, quantum physics, and quantum computing.

A powerful simulation tool

Of particular interest to those of us in quantum computing, the best methods (that we know of) for simulating quantum computers with classical computers rely on tensor networks. Tensor networks provide a nice way of representing the entanglement in a quantum algorithm and how it spreads, which is crucial but generally quite difficult for classical algorithms. In fact, it’s partly tensor networks’ ability to represent entanglement that makes them so powerful for quantum simulation. Importantly, it is our in-house expertise with tensor networks that makes us confident we are indeed moving past classical capabilities.

A theory of evolution

Tensor networks are not only crucial to cutting-edge simulation techniques.  At Quantinuum, we're working on understanding and implementing quantum versions of classical tensor network algorithms, from quantum matrix product states to holographic simulation methods. In doing this, we are leveraging decades of classical algorithm development to advance quantum computing.

A topic of growing interest is the role of tensor networks in QEC, particularly in a process known as decoding. QEC works by encoding information into an entangled state of multiple qubits and using syndrome measurements to detect errors. These measurements must then be decoded to identify the specific error and determine the appropriate correction. This decoding step is challenging—it must be both fast (within the qubit’s coherence time) and accurate (correctly identifying and fixing errors). Tensor networks are emerging as one of the most effective tools for tackling this task.

Looking forward (and backwards, and sideways...)

Tensor networks are more than just a powerful computational tool — they are a bridge between classical and quantum thinking. As this new paper shows, the community’s understanding of tensor networks has matured into a robust foundation for advancing quantum computing, touching everything from simulation and machine learning to error correction and circuit design.

At Quantinuum, we see this as an evolutionary step, not just in theory, but in practice. By collaborating with top minds across academia and industry, we're charting a path forward that builds on decades of classical progress while embracing the full potential of quantum mechanics. This transition is not only conceptual but algorithmic, advancing how we formulate and implement methods utilizing efficiently both classical and quantum computing. Tensor networks aren’t just helping us keep pace with classical computing; they’re helping us to transcend it.

technical
All