In 1952, facing opposition from scientists who disbelieved her thesis that computer programming could be made more useful by using English words, the mathematician and computer scientist Grace Hopper published her first paper on compilers and wrote a precursor to the modern compiler, the A-0, while working at Remington Rand.
Over subsequent decades, the principles of compilers, whose task it is to translate between high level programming languages and machine code, took shape and new methods were introduced to support their optimization. One such innovation was the intermediate representation (IR), which was introduced to manage the complexity of the compilation process, enabling compilers to represent the program without loss of information, and to be broken up into modular phases and components.
This developmental path spawned the modern computer industry, with languages that work across hardware systems, middleware, firmware, operating systems, and software applications. It has also supported the emergence of the huge numbers of small businesses and professionals who make a living collaborating to solve problems using code that depends on compilers to control the underlying computing hardware.
Now, a similar story is unfolding in quantum computing. There are efforts around the world to make it simpler for engineers and developers across many sectors to take advantage of quantum computers by translating between high level coding languages and tools, and quantum circuits — the combinations of gates that run on quantum computers to generate solutions. Many of these efforts focus on hybrid quantum-classical workflows, which allow a problem to be solved by taking advantage of the strengths of different modes of computation, accessing central processing units (CPUs), graphical processing units (GPUs) and quantum processing units (QPUs) as needed.
Microsoft is a significant contributor to this burgeoning quantum ecosystem, providing access to multiple quantum computing systems through Azure Quantum, and a founding member of the QIR Alliance, a cross-industry effort to make quantum computing source code portable across different hardware systems and modalities and to make quantum computing more useful to engineers and developers. QIR offers an interoperable specification for quantum programs, including a hardware profile designed for Quantinuum’s H-Series quantum computers, and has the capacity to support cross-compiling quantum and classical workflows, encouraging hybrid use-cases.
As one of the largest integrated quantum computing companies in the world, Quantinuum was excited to become a QIR steering member alongside partners including Nvidia, Oak Ridge National Laboratory, Quantum Circuits Inc., and Rigetti Computing. Quantinuum supports multiple open-source eco-system tools including its own family of open-source software development kits and compilers, such as TKET for general purpose quantum computation and lambeq for quantum natural language processing.
As founding members of QIR, Quantinuum recently worked with Microsoft Azure Quantum alongside KPMG on a project that involved Microsoft’s Q#, a stand-alone language offering a high level of abstraction and Quantinuum’s System Model H1, Powered by Honeywell. The Q# language has been designed for the specific needs of quantum computing and provides a high-level of abstraction enabling developers to seamlessly blend classical and quantum operations, significantly simplifying the design of hybrid algorithms.
KPMG’s quantum team wanted to translate an existing algorithm into Q#, and to take advantage of the unique and differentiating capabilities of Quantinuum’s H-Series, particularly qubit reuse, mid-circuit measurement and all-to-all connectivity. System Model H1 is the first generation trapped-ion based quantum computer built using the quantum charge-coupled device (QCCD) architecture. KPMG accessed the H1-1 QPU with 20 fully connected qubits. H1-1 recently achieved a Quantum Volume of 32,768, demonstrating a new high-water mark for the industry in terms of computation power as measured by quantum volume.
Q# and QIR offered an abstraction from hardware specific instructions, allowing the KPMG team, led by Michael Egan, to make best use of the H-Series and take advantage of runtime support for measurement-conditioned program flow control, and classical calculations within runtime.
Nathan Rhodes of the KPMG team wrote a tutorial about the project to demonstrate how an algorithm writer would use the KPMG code step-by-step as well as the particular features of QIR, Q# and the H-Series. It is the first time that code from a third party will be available for end users on Microsoft’s Azure portal.
Microsoft recently announced the roll-out of integrated quantum computing on Azure Quantum, an important milestone in Microsoft’s Hybrid Quantum Computing Architecture, which provides tighter integration between quantum and classical processing.
Fabrice Frachon, Principal PM Lead, Azure Quantum, described this new Azure Quantum capability as a key milestone to unlock a new generation of hybrid algorithms on the path to scaled quantum computing.
The team ran an algorithm designed to solve an estimation problem, a promising use case for quantum computing, with potential application in fields including traffic flow, network optimization, energy generation, storage, and distribution, and to solve other infrastructure challenges. The iterative phase estimation algorithm1 was compiled into quantum circuits from code written in a Q# environment with the QIR toolset, producing a circuit with approximately 500 gates, including 111 2-Qubit gates, running across three qubits with one reused three times, and achieving a fidelity of 0.92. This is possible because of the high gate fidelity and the low SPAM error which enables qubit reuse.
The results compare favorably with the more standard Quantum Phase Estimation version described in “Quantum computation and quantum information,” by Michael A. Nielsen and Isaac Chuang.
Quantinuum’s H1 had five capabilities that were crucial to this project:
The project emphasized the importance of companies experimenting with quantum computing, so they can identify any possible IT issues early on, understanding the development environment and how quantum computing integrates with current workflows and processes.
As the global quantum ecosystem continues to advance, collaborative efforts like QIR will play a crucial role in bringing together industrial partners seeking novel solutions to challenging problems, talented developers, engineers, and researchers, and quantum hardware and software companies, which will continue to add deep scientific and engineering knowledge and expertise.
Quantinuum, the world’s largest integrated quantum company, pioneers powerful quantum computers and advanced software solutions. Quantinuum’s technology drives breakthroughs in materials discovery, cybersecurity, and next-gen quantum AI. With over 500 employees, including 370+ scientists and engineers, Quantinuum leads the quantum computing revolution across continents.
At the heart of quantum computing’s promise lies the ability to solve problems that are fundamentally out of reach for classical computers. One of the most powerful ways to unlock that promise is through a novel approach we call Generative Quantum AI, or GenQAI. A key element of this approach is the Generative Quantum Eigensolver (GQE).
GenQAI is based on a simple but powerful idea: combine the unique capabilities of quantum hardware with the flexibility and intelligence of AI. By using quantum systems to generate data, and then using AI to learn from and guide the generation of more data, we can create a powerful feedback loop that enables breakthroughs in diverse fields.
Unlike classical systems, our quantum processing unit (QPU) produces data that is extremely difficult, if not impossible, to generate classically. That gives us a unique edge: we’re not just feeding an AI more text from the internet; we’re giving it new and valuable data that can’t be obtained anywhere else.
One of the most compelling challenges in quantum chemistry and materials science is computing the properties of a molecule’s ground state. For any given molecule or material, the ground state is its lowest energy configuration. Understanding this state is essential for understanding molecular behavior and designing new drugs or materials.
The problem is that accurately computing this state for anything but the simplest systems is incredibly complicated. You cannot even do it by brute force—testing every possible state and measuring its energy—because the number of quantum states grows as a double-exponential, making this an ineffective solution. This illustrates the need for an intelligent way to search for the ground state energy and other molecular properties.
That’s where GQE comes in. GQE is a methodology that uses data from our quantum computers to train a transformer. The transformer then proposes promising trial quantum circuits; ones likely to prepare states with low energy. You can think of it as an AI-guided search engine for ground states. The novelty is in how our transformer is trained from scratch using data generated on our hardware.
Here's how it works:
To test our system, we tackled a benchmark problem: finding the ground state energy of the hydrogen molecule (H₂). This is a problem with a known solution, which allows us to verify that our setup works as intended. As a result, our GQE system successfully found the ground state to within chemical accuracy.
To our knowledge, we’re the first to solve this problem using a combination of a QPU and a transformer, marking the beginning of a new era in computational chemistry.
The idea of using a generative model guided by quantum measurements can be extended to a whole class of problems—from combinatorial optimization to materials discovery, and potentially, even drug design.
By combining the power of quantum computing and AI we can unlock their unified full power. Our quantum processors can generate rich data that was previously unobtainable. Then, an AI can learn from that data. Together, they can tackle problems neither could solve alone.
This is just the beginning. We’re already looking at applying GQE to more complex molecules—ones that can’t currently be solved with existing methods, and we’re exploring how this methodology could be extended to real-world use cases. This opens many new doors in chemistry, and we are excited to see what comes next.
Last year, we joined forces with RIKEN, Japan's largest comprehensive research institution, to install our hardware at RIKEN’s campus in Wako, Saitama. This deployment is part of RIKEN’s project to build a quantum-HPC hybrid platform consisting of high-performance computing systems, such as the supercomputer Fugaku and Quantinuum Systems.
Today, a paper published in Physical Review Research marks the first of many breakthroughs coming from this international supercomputing partnership. The team from RIKEN and Quantinuum joined up with researchers from Keio University to show that quantum information can be delocalized (scrambled) using a quantum circuit modeled after periodically driven systems.
"Scrambling" of quantum information happens in many quantum systems, from those found in complex materials to black holes. Understanding information scrambling will help researchers better understand things like thermalization and chaos, both of which have wide reaching implications.
To visualize scrambling, imagine a set of particles (say bits in a memory), where one particle holds specific information that you want to know. As time marches on, the quantum information will spread out across the other bits, making it harder and harder to recover the original information from local (few-bit) measurements.
While many classical techniques exist for studying complex scrambling dynamics, quantum computing has been known as a promising tool for these types of studies, due to its inherently quantum nature and ease with implementing quantum elements like entanglement. The joint team proved that to be true with their latest result, which shows that not only can scrambling states be generated on a quantum computer, but that they behave as expected and are ripe for further study.
Thanks to this new understanding, we now know that the preparation, verification, and application of a scrambling state, a key quantum information state, can be consistently realized using currently available quantum computers. Read the paper here, and read more about our partnership with RIKEN here.
In our increasingly connected, data-driven world, cybersecurity threats are more frequent and sophisticated than ever. To safeguard modern life, government and business leaders are turning to quantum randomness.
The term to know: quantum random number generators (QRNGs).
QRNGs exploit quantum mechanics to generate truly random numbers, providing the highest level of cryptographic security. This supports, among many things:
Quantum technologies, including QRNGs, could protect up to $1 trillion in digital assets annually, according to a recent report by the World Economic Forum and Accenture.
The World Economic Forum report identifies five industry groups where QRNGs offer high business value and clear commercialization potential within the next few years. Those include:
In line with these trends, recent research by The Quantum Insider projects the quantum security market will grow from approximately $0.7 billion today to $10 billion by 2030.
Quantum randomness is already being deployed commercially:
Recognizing the value of QRNGs, the financial services sector is accelerating its path to commercialization.
On the basis of the latter achievement, we aim to broaden our cybersecurity portfolio with the addition of a certified randomness product in 2025.
The National Institute of Standards and Technology (NIST) defines the cryptographic regulations used in the U.S. and other countries.
This week, we announced Quantum Origin received NIST SP 800-90B Entropy Source validation, marking the first software QRNG approved for use in regulated industries.
This means Quantum Origin is now available for high-security cryptographic systems and integrates seamlessly with NIST-approved solutions without requiring recertification.
The NIST validation, combined with our peer-reviewed papers, further establishes Quantum Origin as the leading QRNG on the market.
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It is paramount for governments, commercial enterprises, and critical infrastructure to stay ahead of evolving cybersecurity threats to maintain societal and economic security.
Quantinuum delivers the highest quality quantum randomness, enabling our customers to confront the most advanced cybersecurity challenges present today.