

It’s believed that quantum computing will transform the way we solve chemistry problems, and the Quantinuum scientific team continues to push the envelope towards making that a reality.
In their latest research paper published on the arXiv, Quantinuum scientists describe a new hybrid classical-quantum solver for chemistry. The method they developed can model complex molecules at a new level of efficiency and precision.
Dr. Michał Krompiec, Scientific Project Manager, and his colleague Dr. David Muñoz Ramo, Head of Quantum Chemistry, co-authored the paper, "Strongly Contracted N-Electron Valence State Perturbation Theory Using Reduced Density Matrices from a Quantum Computer".
The implications are significant as their innovation “tackles one of the biggest bottlenecks in modelling molecules on quantum computers,” according to Dr. Krompiec.
Quantum computers are a natural platform to solve chemistry problems. Chemical molecules are made of many interacting electrons, and quantum mechanics can describe the behavior and energies of these electrons.
As Dr. Krompiec explains, “nature is not classical, it is quantum. We want to map the quantum system of interacting electrons into a quantum system of interacting qubits, and then solve it.”
Solving the full picture of electron interactions is extremely difficult, but fortunately it is not always necessary. Scientists usually simplify the task by focusing on the active space of the molecule, a smaller subset of the problem which matters most.
Even with these simplifications, difficulties remain. One challenge is carefully choosing this smaller subset, which describes strongly correlated electrons and is therefore more complex. Another challenge is accurately solving the rest of the system. Solving the chemistry of the complex subset can often be done from perturbation theory using so-called “multi-reference” methods.
In their work, the Quantinuum team came up with a new multi-reference technique. They maintain that only the strongly correlated part of the molecule should be calculated on a quantum computer. This is important, as this part usually scales exponentially with the size of the molecule, making it classically intractable.
The quantum algorithm they used on this part relied on measuring reduced density matrices and feeding them into a multi-reference perturbation theory calculation, a combination that had never been used in this context. Implementing the quantum electronic structure solver on the active space and using measured reduced density matrices makes the problem less computationally expensive and the solution more accurate.
The team tested their workflow on two molecules - H2 and Li2 – using Quantinuum’s hybrid solver implemented in the InQuanto quantum computational chemistry platform and IBM’s 27-qubit device. Quantinuum software is platform inclusive and is often tested on both its own H Series ion-trap quantum systems as well as others.
The non-strongly correlated regions of the molecules were run classically, as they would not benefit from a quantum speedup. The team’s results showed excellent agreement with previous models, meaning their method worked. Beyond that, the method showed great promise for reaching new levels of speed and accuracy for larger molecules.
The future impact of this work could create a new paradigm to perform quantum chemistry. The authors of the paper believe it may represent the best way of computing dynamic correlation corrections to active space-type quantum methods.
As Dr. Krompiec said, “Quantum chemistry can finally be solved with an application of a quantum solver. This can remove the factorial scaling which limits the applicability of this rigorous method to a very small subsystem.”
The idea to use a multi-reference method along with reduced density matrix measurement is quite novel and stems from the diverse backgrounds of the team at Quantinuum. It is a unique application of well-known quantum algorithms to a set of theoretical quantum chemistry problems.
The use cases are vast. Analysis of catalyst and material properties may first benefit from this new method, which will have a tremendous impact in the automotive, aerospace, fine chemicals, semiconductor, and energy industries.
Implementing this method on real hardware is limited by the current noise levels. But as the quality of the qubits increases, the method will unleash its full potential. Quantinuum’s System Model H1 trapped-ion hardware, Powered by Honeywell, benefits from high fidelity qubits, and will be a valuable resource for quantum chemists wishing to follow this work.
This hybrid quantum-classical method promises a path to quantum advantage for important chemistry problems, as machines become more powerful.
As Dr. Krompiec summarizes, “we haven’t just created a toy model that works for near-term devices. This is a fundamental method that will still be relevant as quantum computers continue to mature.”
Quantinuum, the world’s largest integrated quantum company, pioneers powerful quantum computers and advanced software solutions. Quantinuum’s technology drives breakthroughs in materials discovery, cybersecurity, and next-gen quantum AI. With over 500 employees, including 370+ scientists and engineers, Quantinuum leads the quantum computing revolution across continents.
Quantum computing is entering a new era. As systems move from Noisy Intermediate-Scale Quantum (NISQ) toward Fault-Tolerant Application-Scale Quantum (FASQ), traditional metrics like qubit count, gate fidelity, and gate speed are no longer enough to describe what a machine can actually deliver.
Developed by Sandia National Laboratories, with input from Quantinuum and NVIDIA, QUOPS—the Quantum Universal Operations Performance System—is a common, architecture-agnostic benchmark for measuring quantum performance across both physical- and logical-qubit systems on the path toward quantum utility.
QUOPS can be applied to different architectures, codes, modalities, and levels of fault tolerance. QUOPS runs the same randomized workloads across different computational shapes, measures whether each workload succeeds, identifies the boundary of a system’s capability region, and reports two summary metrics:
The result is a direct measure of how much computation a system can perform and how quickly it can do so. Together, these measurements provide a two-dimensional view of capability while reducing system performance to a common currency: quantum operations.
Component-level metrics remain essential for engineering. Qubit count, two-qubit fidelity, and gate speed can reveal control errors, crosstalk, leakage, connectivity constraints, and other system limitations. But they do not necessarily predict system-level performance.
Fault tolerance makes this gap even larger. Physical operations become logical computation with the addition of logical encoding, syndrome measurement, decoding, logical gate construction, magic-state production, routing, and control. Ultimately, this means that fault tolerance expands the relevant currencies of computation. Code distance, logical fidelity, magic-state throughput, decoding, connectivity, and space-time volume can matter far more for performance than raw qubit count or individual gate speeds.
This creates a growing challenge for buyers, governments, and researchers. As organizations move from experimentation toward larger-scale and potentially on-premise quantum systems, they need to know a simple thing:
What computation can a machine actually execute successfully?
QUOPS addresses that question by measuring the integrated system rather than inferring performance from individual components.
This is particularly important as the field considers workloads requiring roughly 10⁹–10¹² operations on thousands of qubits. Today's measured capabilities are still orders of magnitude smaller; QUOPS turns that gap into a measurable quantity.
QUOPS can also provide a practical layer for quantum procurement and planning.
HPC centers need to understand when quantum computing will become useful for real workloads. Customers may have a goal of procuring a system that can, for example, run a trillion error-free operations. Today, answering these questions can require complex resource estimates that depend on hardware modality, QEC code, magic-state factories, decoding, compilation, and other architectural choices.
In both cases, QUOPS provides a simpler system-level reference point: Q describes the size of computation a machine can execute, while Ω describes its effective throughput. Furthermore, because QUOPS is architecture-neutral and includes anti-gaming provisions, it can also help buyers compare competing systems without relying solely on vendor-selected metrics or announcements.
While QUOPS is a new benchmark, it has already been measured on several vendors’ hardware. This marks an important step for our industry: we can now compare vendors directly, assessing their capabilities in a way that flattens the differences introduced by modality and architecture choices.
Figure 1. The QUOPS capability region and score for state-of-the-art processors from Quantinuum, Google, and IBM (adapted from Figure 2 of the scientific publication co-authored by Quantinuum, Sandia National Laboratories, and NVIDIA). QUOPS specifies a random circuit construction that can be built for a specified width (number of qubits) and size (number of quantum gates). A set of circuits is run at several width and size points and the average fidelity of those circuits are measured and compared to a predefined threshold. Each labeled point above represents experimental data from QUOPS circuits that passed the threshold with high confidence. The lines are filled capability limits of each machine between the points. The stars indicate the QUOPS score (Q), which is the experimental data point that passes the threshold with maximum size inside the shaded cone of width2 ≤ size ≤ width3.
Figure 2. The QUOPS score (Q) vs rate (Ω) for state-of-the-art processors from Quantinuum, Google, and IBM (adapted from Figure 2 of the QUOPS scientific publication co-authored by Quantinuum, Sandia National Laboratories, and NVIDIA). Each point is the maximum QUOPS circuit size that passes the threshold within the specified cone and rate that it was run. The dashed lines indicate the extrapolated effect of error mitigation, which attenuates the rate by including the shot overhead needed for general-purpose error mitigation. The gradient lines show the estimated runtime of a circuit at a given score and rate.
Figures 1 and 2 show how QUOPS quantifies the capability tradeoffs between different systems. Willow and Boston are superconducting systems with very fast gate speeds but limited connectivity, while Helios is a trapped-ion QCCD system with effective all-to-all connectivity but much slower gates. Willow and Boston have smaller capability regions and QUOPS scores but higher QUOPS rates; while Helios reaches larger capability regions and QUOPS scores but lower QUOPS rates. All three systems have the ability to trade speed for larger circuits with error mitigation. This is commonly assumed in the community but is nicely quantified with the QUOPS rate, which accounts for the corresponding sampling overheads of general error mitigation techniques (as shown by the dashed lines in Figure 2).
QUOPS will not replace every quantum benchmark. The field will continue to need application-specific suites, component-level measurements, hybrid-HPC benchmarks, and independent verification.
QUOPS instead serves as a common system-level yardstick that can make roadmaps more comparable, procurement more objective, and progress easier to track.
We are calling on vendors to report QUOPS metrics (Q, Ω) and capability regions alongside existing metrics, buyers and agencies to consider QUOPS thresholds in RFPs, and researchers to contribute fault-tolerant architectures and resource estimates.
As quantum computers become fault tolerant, success will no longer be defined simply by how many qubits a machine contains or how low its error rates are.
It will be defined by the computation the machine can deliver.
QUOPS is a step toward measuring that capability—and toward giving the quantum industry a benchmark built for the era ahead.
Building a quantum computer is one thing. Showing that it is genuinely using quantum mechanics is another.
A new experiment, just published in Nature Communications, takes a fresh approach to that question. Instead of relying on entanglement or the complex calculations often used to benchmark quantum computers, researchers designed a simple game (initially published in Physical Review Letters) that tests something more fundamental: quantum superposition.
Using superposition, the team constructed a game where quantum mechanics provides a provable advantage over classical approaches. Once the game was set, the team ran it on real hardware. The results showed a clear performance gap between the best possible classical system and our System Model H2 – a gap that only grew as the test became more difficult.
The game is played by a single player with access to a computer. The player receives a quantum state representing a set of numbers—for example, {0, 1, 5, 7}. Their goal is to return a number that belongs to the complement of that set: {2, 3, 4, 6}.
That sounds simple. But as the size of the sets grows, something remarkable happens.
A classical strategy needs to test many numbers to succeed. A quantum strategy, however, succeeds in one step. The authors show that the quantum strategy has a score that grows exponentially faster.
Importantly, this isn't based on an assumption that this problem is difficult for classical computers. The separation is mathematically proven. In other words, the researchers can show that the quantum advantage exists without relying on unproven assumptions from complexity theory.
Using our System Model H2, the experimenters were able to confirm the theoretically derived separation between the quantum and the classical strategy (up to the largest sizes they could fit on the quantum processor) with high confidence – showing that the violation remained close to exponential.
Many famous experiments testing quantum behavior rely on entanglement and non-locality, where multiple parties share parts of a quantum system.
This experiment is different.
There is only one player, who has access to the entire quantum system. The advantage comes from superposition—the ability of a quantum system to exist in a combination of states until it is measured.
That distinction matters because it provides another way to ask whether a quantum computer is actually behaving quantum mechanically.
The researchers turned their game into an experimental test and ran thousands of different circuits on Quantinuum's System Model H2. The scores they observed were close to the theoretical predictions for a quantum strategy.
One of the challenges with existing quantum-computing demonstrations is figuring out whether the machine really produced the result it was supposed to produce.
For example, random circuit sampling can be extremely difficult to verify classically as systems become larger. That creates a tension: you want to demonstrate that a quantum computer is doing something a classical computer cannot easily reproduce, but you also need a practical way to check the result.
The complement-sampling game offers a different approach. The violation of classical performance can be efficiently verified with a classical computer.
That makes the test potentially more scalable: you don't need to reproduce the entire quantum computation on a classical computer just to determine whether the machine demonstrated non-classical behavior.
The deeper message of the experiment is that demonstrating a quantum computer isn't simply about having qubits.
A convincing demonstration should show that the machine is exploiting properties that genuinely distinguish quantum computation from classical computation. Here, the researchers focus on one of those defining properties—superposition—and construct a game where quantum mechanics provides a provable advantage.
This first experimental demonstration of complement sampling doesn't close every possible loophole, which is common for this sort of experiment – closing the major experimental loopholes in Bell-inequality tests took decades—a body of work that ultimately contributed to the 2022 Nobel Prize in Physics. The researchers explicitly note that the implementation relies on assumptions about how the input state is prepared, so the experimental results should be interpreted with some caution.
Still, the work provides a new way to probe the boundary between classical and quantum computation.
And that may be the most interesting part: rather than asking only “How many qubits does the machine have?”, we can ask a more meaningful question—
“What can this machine do that only a quantum system can?”
That is ultimately what it takes for a quantum computer to actually be quantum.
The NISQ1 era is coming to an end. At Quantinuum, we’ve already demonstrated numerous QEC codes, all the primitives needed for logical computation, steadily declining logical error rates, and full computations at the logical level.
But there’s still a way to go. One of the defining challenges over the coming years will be putting it all together into a usable – and scalable – fault tolerant architecture. Today, we are excited to announce that we have experimentally validated one of our own leading candidates for such an architecture, the Helix code.
With this demonstration, we have put all the pieces together: logical memory, logical computation, a heterogenous code architecture that optimizes for magic vs gates, all with super efficient operations and record-breaking2 fidelity.
The delicate nature of qubits gives them their strength – they can be entangled, placed into superpositions, and even teleported. However, this comes at a cost: on the hardware level, quantum bits (qubits) will always be noisier than classical bits.
Enter quantum error correction (QEC). QEC moves us past prohibitive physical noise to fidelities that really matter; where industrial workflows and scientific discovery live. Our field has been hard at work to realize - and optimize - QEC, and we are finally starting to reap the fruits of that labor.
However, for the most part, this work has taken shape only a few pieces at a time: a demonstration of fault tolerant gates here or memory there, sometimes even a full fault-tolerant algorithm, but rarely do we see demonstrations at the architectural scale needed to build our next generation of machines.
The difficulty is that encoding and performing fault-tolerant computation costs considerable space (qubit number) and time (circuit complexity), which QEC researchers summarize with a “spacetime volume”.
The Helix code was custom-designed to usher in the next generation of fault tolerance.
Using our reconfigurable qubits, we designed Helix to minimize its spacetime volume by employing more exotic entanglement schemes compared to traditional codes (imagine cat’s cradle compared to a simple, 2D net). This entanglement complexity is impossible with processors that don’t have reconfigurable connectivity.
Ultimately, this translates to a code that requires fewer physical qubits per logical qubit, while also giving you fast and simple computing.

In general, gates between logical qubits can be quite difficult because logical qubits are composed of physical qubits that are entangled together in some specific way. Sometimes, a single physical qubit may even be shared between multiple logical qubits, as is the case with codes that offer lots of logical qubits per physical qubit. Performing gates across these complex structures can be tricky, and can take a lot of individual operations on physical qubit pairs to accomplish.
There are two major exceptions. The first, called a transversal gate, is where the logical operation maps directly onto the physical one: you just perform a regular 2-qubit gate between each physical qubit in each logical qubit.
The second is simpler still: gates can be accomplished by simple software-level qubit relabeling (eg simply renaming qubit A to qubit B), combined with easy, single qubit gates. This type of automorphism, or permutation-based gate, is particularly elegant.
The Helix code makes heavy use of transversal and automorphism gates, making it considerably faster and easier to compute with than a lot of other options. Ultimately, this translates to a significant reduction in both space (qubit) and time (circuit complexity) overheads: less space is needed for block encoding and ancilla; and time is drastically reduced when simple software relabeling or transversal gates are performed in the place of expensive protocols like lattice surgery.

Experiment 1: Logical Memory
The team started by showing that the Helix code can successfully preserve encoded quantum information for extended periods of time.
To show this, the team started with their logical qubits in a given state. Then, they performed 20 rounds of syndrome extraction, paying special attention to leakage (a dominant source of error on Helios). To remove leakage, the team leveraged Helios’ new leakage repump capacity, as well as circuit-level leakage reduction units.
Result: per qubit, per round, they achieved an error rate of 4.6 x 10-5, with no post selection.
This amounts to a block logical error per round of 9.3 x 10-5, with no post selection. With a small amount of post selection (0.5%), the block logical error per round was reduced to 1.9 x 10-5.
Quantum memory is one of the most fundamental building blocks of a fault-tolerant quantum computer. A useful quantum processor must be able to preserve quantum information long enough to perform the computation, error correction, and communication required by larger algorithms.
These results prove that encoded quantum information can be preserved with a lower error rate than the underlying physical operations – all without needing post selection.
Experiment 2: Logical Computation
A central feature of the Helix logical architecture is that encoding multiple logical qubits does not require correspondingly expensive logical computation. By construction, this code has a variety of logical gates all implementable with only physical single-qubit gates and qubit relabeling. These ‘SWAP-transversal’, or ‘automorphism’, gates provide the ability to do some logical circuits essentially for free, as permutations are realized by simple ion-transport and software level relabeling.
The team experimentally tested the code’s computational abilities by benchmarking the complete logical Clifford group (i.e., all gates except for T gates) while interleaving up to 27 rounds of active adaptive syndrome extraction.
Result: 2.8 x 10-4 logical error rate per Clifford gate, a significant improvement (4.28x) over Helios’ physical 2-qubit Clifford error rate, again achieved without post selection.
This impressive result is partially enabled by the team’s clever adaptive syndrome extraction (ASE) technique. Their ASE technique reduces the number of physical gates required per logical gate by about 33%. This pruning also shortens the physical run time, reducing the ‘wall clock duration’ by about 23%. Both gates and idling contribute significantly to errors, so these reductions translate to a lower logical error rate.
This experiment proves the Helix code’s ability to compute, all while showing significant improvement over the physical level with no post selection. In addition, this marks the first demonstration of randomized benchmarking on a code encoding more than one logical qubit, an important milestone for our community.
Experiment 3: Universality via Logical Entanglement Across Different Codes
Clifford gates alone are insufficient for universal fault-tolerant computation; our QEC architecture must also provide access to non-Clifford resource states (often called “magic”). While the Helix code has many desirable features in terms of Clifford gates, it’s sub-optimal for preparing magic states. Rather than forcing the Helix code to work in this regime, we developed our architecture to employ two codes; one for Clifford gates and memory, and one for magic state preparation. Using different codes each optimized for their own tasks, called a heterogenous architecture, makes the entire assembly considerably more efficient and cost effective.
The trick that makes it all possible is something called chain-mapping, that allows the QPU to smoothly switch between underlying encoding schemes. To test this, the team used a rotated surface code for magic state generation, which would then be injected into the computational (Helix) code to generate non-Clifford gates (enabling fault tolerant universal computation).
Rather than performing magic state injection directly, the team wanted to benchmark the interface (the chain-map). To do this, they used their chain-mapped gates to prepare a three logical qubit GHZ state that spans the two different codes. The resulting GHZ state contained 1 logical qubit from the surface code and two from the Helix code, making for a truly heterogeneous structure.
Result: The logical GHZ state had a fidelity lower bound of 99.925%, and an upper bound of 99.975%. The lower bound exceeded the physical baseline, making all three experiments better than their physical counterparts.

This experiment demonstrates one of our key architectural advantages: using our reconfigurable connectivity to employ multiple QEC encodings in a single fault tolerant architecture, improving our efficiency and reducing qubit costs.
The quantum computing industry has proposed many approaches to error correction. This paper marks one of the first experimentally validated plans for a QEC architecture. With the low logical error rates (all improving on the physical baseline), the practical logical operations (which drastically reduce qubit costs and compute time), and real commercial hardware performance, this result helps to prove that we will deliver on our roadmap.
A crucial element of this demonstration is that these results were obtained on our commercial hardware. This is not a result from a testbed, or a result from hardware that has limited functionality. This is a result from the same computer as our customers use for their own research.
Furthermore, simulations indicate that the improvements in physical fidelity we expect from moving from Helios to Apollo will bring logical error rates in line with our roadmap targets. Because logical error rates depend strongly on physical error rates, Apollo’s expected improvements at the physical level should translate directly into lower logical error rates. Importantly, we expect to achieve these gains without increasing the code distance or using additional physical qubits per logical qubit.

Building a fault-tolerant quantum computer requires solving multiple engineering challenges. In this result we have proven our path to a scalable QEC architecture, showing not just one-off results on test stand hardware, but a harmonious whole consisting of:
✓ A candidate architectural code
✓ Logical memory
✓ Logical computation
✓ A path to magic
✓ Multiple encodings in one architecture
✓ Commercial hardware compatibility
By validating our fault-tolerant architecture on real commercial hardware, Quantinuum has taken a significant step toward Apollo - and toward quantum computers capable of solving meaningful problems at scale.

1 Noisy Intermediate-Scale Quantum
2 Based on a study of existing literature