Developing “Killer Apps” for Quantum Computing
Logistics, Supply Chain and Routing
By Kevin Jackson for Quantinuum
The world is a lot smaller than it was in the previous century – or even in the previous decade.
Customers are now accustomed to a wide variety of products that can be delivered from distributors all over the globe. While this is a great opportunity for suppliers, it also presents a challenge in the form of supply chain, logistics, routing, and optimization.
How can distribution companies continue to serve the needs of their customers in the most efficient and effective way possible? This may seem like a simple question, but it becomes a complex computational problem when trying to account for all the variables that can occur within a distribution network.
What’s more, classical computers simply cannot adequately perform this optimization calculation in real-world scenarios. Because of the number of variables, the math just runs too slow.
That said, new work in quantum computing has shown promise in applications within the optimization field. To that end, we interviewed Quantinuum’s Megan Kohagen and Dr. Mattia Fiorentini to better understand how quantum computing could to optimized logistics and supply chains.
Kohagen and Fiorentini are participating in a panel about quantum computing at Manifest: The Future of Logistics conference this week in Las Vegas, Nevada.
Beyond classical computing
When it comes to optimization it is all about maximizing or minimizing an objective. A good example is a company that delivers goods and products but owns a limited number of trucks. To improve efficiency and minimize costs, the company needs to maximize the number of objects its trucks carry and identify the shortest routes between deliveries.
“You have all these constraints, you have your objective, and you’ve got to make decisions,” said Kohagen, an optimization researcher. “The decisions end up being things like how many goods you are going to send between your distribution centers and your stores? Each of these optimization problems, even if you consider them separately, are hard problems. The technical term is that they’re (non-deterministic polynomial)-hard because you’re dealing with discrete things. For example, I can’t send half a T-shirt to my customer. I can only operate with whole integers.”
Fiorentini expands on this: “In logistics, we cannot leave anyone behind. If we need to deliver medicine, we cannot decide ‘the villages with less than 1,000 people – we don’t supply them. There are too many, and not enough people live there’. That’s not an option in today’s world.”
Today’s computers struggle to solve these NP-hard optimization problems because of the number of ever-changing variables. Consider the much-studied Traveling Salesperson Problem, which is often used to illustrate the complexity of managing logistics, routing, and supply chains.
This is a theoretical problem where a machine is tasked with finding the shortest route between an identified list of cities that a “salesperson” must visit before returning to the point of origin. This problem is simple enough with only a few cities, but it becomes exponentially harder as more locations are added, and other factors such as multiple salespeople, weather conditions, and unforeseen events arise.
Classical computers can solve this theoretical problem for a single salesperson traveling to thousands of cities. But this scenario is not realistic, and this is where classical computers begin to struggle.
“The Traveling Salesperson Problem is not very representative of what happens in the real world,” Kohagen said. “For example, with online ordering so prevalent, a retailer has orders coming in constantly. They must determine how to efficiently retrieve those items from the warehouse, pack them into the trucks, and then transport them to the customers.”
Today, the reality of an extended supply chain or distribution network is beyond what the best classical computer can solve. Quantum computers harness unique properties of quantum physics that enable them to examine all possible answers simultaneously and then concentrate the probable output of the computation onto the best option.
“Classical is a great technology, but it doesn’t cut it here,” said Fiorentini, who develops and tests quantum algorithms for optimization. “Quantum is the best alternative to classical computing that we have.“
The quantum computing opportunity
Optimization problems have long been viewed as “killer applications” for quantum computing and research conducted by Fiorentini, Kohagen and others has begun to prove that.
Fiorentini believes it is time for decision makers to explore and invest in quantum-enabled solutions for optimization problems. “There are two decisions here for decision makers,” he said. “We either give up on the problem and say, ‘we’ll just do the best we can with a classical solution, or we start allocating a budget for really developing quantum technology.”
Quantum computing is expanding rapidly and is poised to disrupt markets such as optimization. A similar situation is the power sector, which is experiencing major disruptions due to innovations in renewable energy resources, energy storage, and regulatory reform.
Every technology has a tipping point, and all signs point to a current trend in quantum computing moving rapidly to real-world applications in optimization.
“There are a lot of algorithms being developed for optimization right now,” said Kohagen. “If you really want to advance your business with quantum methods for logistics or supply chain, this is the moment to start. Decision makers must act quickly. Those that seize the opportunity before others will have a major advantage over those who lag.”
“As quantum computers continue to scale in computational power, they’ll be able to handle increasingly complex calculations to deliver more robust and optimized supply chain solutions,” said Tony Uttley, President and COO of Quantinuum.
“We’re excited by the acceleration of our System Model H1 technologies, Powered by Honeywell. Measured in terms of qubit number as well as quantum volume, we’re meeting our commitment to increase performance by a factor of 10X each year,” he said. “Alongside other revolutionary advances such as real-time error correction, we look forward to supporting the commercialization of quantum applications that will change the way logistical challenges are met. In fact, within the coming few months we’ll be sharing more exciting news regarding our latest technological achievements.”
Want to learn about our work to develop quantum-enabled optimization solutions for companies? Contact our experts
About Quantinuum
Quantinuum, the world’s largest integrated quantum company, pioneers powerful quantum computers and advanced software solutions. Quantinuum’s technology drives breakthroughs in materials discovery, cybersecurity, and next-gen quantum AI. With over 500 employees, including 370+ scientists and engineers, Quantinuum leads the quantum computing revolution across continents.
If we are to create ‘next-gen’ AI that takes full advantage of the power of quantum computers, we need to start with quantum native transformers. Today we announce yet again that Quantinuum continues to lead by demonstrating concrete progress — advancing from theoretical models to real quantum deployment.
The future of AI won't be built on yesterday’s tech. If we're serious about creating next-generation AI that unlocks the full promise of quantum computing, then we must build quantum-native models—designed for quantum, from the ground up.
Around this time last year, we introduced Quixer, a state-of-the-art quantum-native transformer. Today, we’re thrilled to announce a major milestone: one year on, Quixer is now running natively on quantum hardware.
Why this matters: Quantum AI, born native
This marks a turning point for the industry: realizing quantum-native AI opens a world of possibilities.
Classical transformers revolutionized AI. They power everything from ChatGPT to real-time translation, computer vision, drug discovery, and algorithmic trading. Now, Quixer sets the stage for a similar leap — but for quantum-native computation. Because quantum computers differ fundamentally from classical computers, we expect a whole new host of valuable applications to emerge.
Achieving that future requires models that are efficient, scalable, and actually run on today’s quantum hardware.
That’s what we’ve built.
What makes Quixer different?
Until Quixer, quantum transformers were the result of a brute force “copy-paste” approach: taking the math from a classical model and putting it onto a quantum circuit. However, this approach does not account for the considerable differences between quantum and classical architectures, leading to substantial resource requirements.
Quixer is different: it’s not a translation – it's an innovation.
With Quixer, our team introduced an explicitly quantum transformer, built from the ground up using quantum algorithmic primitives. Because Quixer is tailored for quantum circuits, it's more resource efficient than most competing approaches.
As quantum computing advances toward fault tolerance, Quixer is built to scale with it.
What’s next for Quixer?
We’ve already deployed Quixer on real-world data: genomic sequence analysis, a high-impact classification task in biotech. We're happy to report that its performance is already approaching that of classical models, even in this first implementation.
This is just the beginning.
Looking ahead, we’ll explore using Quixer anywhere classical transformers have proven to be useful; such as language modeling, image classification, quantum chemistry, and beyond. More excitingly, we expect use cases to emerge that are quantum-specific, impossible on classical hardware.
This milestone isn’t just about one model. It’s a signal that the quantum AI era has begun, and that Quantinuum is leading the charge with real results, not empty hype.
Stay tuned. The revolution is only getting started.
Our team is participating in ISC High Performance 2025 (ISC 2025) from June 10-13 in Hamburg, Germany!
As quantum computing accelerates, so does the urgency to integrate its capabilities into today’s high-performance computing (HPC) and AI environments. At ISC 2025, meet the Quantinuum team to learn how the highest performing quantum systems on the market, combined with advanced software and powerful collaborations, are helping organizations take the next step in their compute strategy.
Quantinuum is leading the industry across every major vector: performance, hybrid integration, scientific innovation, global collaboration and ease of access.
- Our industry-leading quantum computer holds the record for performance with a Quantum Volume of 2²³ = 8,388,608 and the highest fidelity on a commercially available QPU available to our users every time they access our systems.
- Our systems have been validated by a #1 ranking against competitors in a recent benchmarking study by Jülich Research Centre.
- We’ve laid out a clear roadmap to reach universal, fully fault-tolerant quantum computing by the end of the decade and will launch our next-generation system, Helios, later this year.
- We are advancing real-world hybrid compute with partners such as RIKEN, NVIDIA, SoftBank, STFC Hartree Center and are pioneering applications such as our own GenQAI framework.
Exhibit Hall
From June 10–13, in Hamburg, Germany, visit us at Booth B40 in the Exhibition Hall or attend one of our technical talks to explore how our quantum technologies are pushing the boundaries of what’s possible across HPC.
Presentations & Demos
Throughout ISC, our team will present on the most important topics in HPC and quantum computing integration—from near-term hybrid use cases to hardware innovations and future roadmaps.
Multicore World Networking Event
- Monday, June 9 | 7:00pm – 9:00 PM at Hofbräu Wirtshaus Esplanade
In partnership with Multicore World, join us for a Quantinuum-sponsored Happy Hour to explore the present and future of quantum computing with Quantinuum CCO, Dr. Nash Palaniswamy, and network with our team.
Register here
H1 x CUDA-Q Demonstration
- All Week at Booth B40
We’re showcasing a live demonstration of NVIDIA’s CUDA-Q platform running on Quantinuum’s industry-leading quantum hardware. This new integration paves the way for hybrid compute solutions in optimization, AI, and chemistry.
Register for a demo
HPC Solutions Forum
- Wednesday, June 11 | 2:20 – 2:40 PM
“Enabling Scientific Discovery with Generative Quantum AI” – Presented by Maud Einhorn, Technical Account Executive at Quantinuum, discover how hybrid quantum-classical workflows are powering novel use cases in scientific discovery.
See You There!
Whether you're exploring hybrid solutions today or planning for large-scale quantum deployment tomorrow, ISC 2025 is the place to begin the conversation.
We look forward to seeing you in Hamburg!
Quantinuum has once again raised the bar—setting a record in teleportation, and advancing our leadership in the race toward universal fault-tolerant quantum computing.
Last year, we published a paper in Science demonstrating the first-ever fault-tolerant teleportation of a logical qubit. At the time, we outlined how crucial teleportation is to realize large-scale fault tolerant quantum computers. Given the high degree of system performance and capabilities required to run the protocol (e.g., multiple qubits, high-fidelity state-preparation, entangling operations, mid-circuit measurement, etc.), teleportation is recognized as an excellent measure of system maturity.
Today we’re building on last year’s breakthrough, having recently achieved a record logical teleportation fidelity of 99.82% – up from 97.5% in last year’s result. What’s more, our logical qubit teleportation fidelity now exceeds our physical qubit teleportation fidelity, passing the break-even point that establishes our H2 system as the gold standard for complex quantum operations.
This progress reflects the strength and flexibility of our Quantum Charge Coupled Device (QCCD) architecture. The native high fidelity of our QCCD architecture enables us to perform highly complex demonstrations like this that nobody else has yet to match. Further, our ability to perform conditional logic and real-time decoding was crucial for implementing the Steane error correction code used in this work, and our all-to-all connectivity was essential for performing the high-fidelity transversal gates that drove the protocol.
Teleportation schemes like this allow us to “trade space for time,” meaning that we can do quantum error correction more quickly, reducing our time to solution. Additionally, teleportation enables long-range communication during logical computation, which translates to higher connectivity in logical algorithms, improving computational power.
This demonstration underscores our ongoing commitment to reducing logical error rates, which is critical for realizing the promise of quantum computing. Quantinuum continues to lead in quantum hardware performance, algorithms, and error correction—and we’ll extend our leadership come the launch of our next generation system, Helios, in just a matter of months.