JPMorgan Chase, Argonne National Laboratory and Quantinuum Show Theoretical Quantum Speedup with the Quantum Approximate Optimization Algorithm
New York, New York, Broomfield, Colorado, Lemont, Illinois, May 29th, 2024 — In a new paper in Science Advances on May 29, researchers at JPMorgan Chase, the U.S. Department of Energy’s (DOE) Argonne National Laboratory and Quantinuum have demonstrated clear evidence of a quantum algorithmic speedup for the quantum approximate optimization algorithm (QAOA).
This algorithm has been studied extensively and has been implemented on many quantum computers. It has potential applications in fields such as logistics, telecommunications, financial modeling, and materials science.
“This work is a significant step towards reaching quantum advantage, laying the foundation for future impact in production,” says Marco Pistoia, Head of Global Technology Applied Research at JPMorgan Chase.
The team examined whether a quantum algorithm with low implementation costs could provide a quantum speedup over the best-known classical methods. QAOA was applied to the Low Autocorrelation Binary Sequences (LABS) problem, which has significance in understanding the behavior of physical systems, signal processing and cryptography. The study showed that if the algorithm was asked to tackle increasingly larger problems, the time it would take to solve them would grow at a slower rate than that of a classical solver.
To explore the quantum algorithm’s performance in an ideal noiseless setting, JPMorgan Chase and Argonne jointly developed a simulator to evaluate the algorithm’s performance at scale. It was built on the Polaris supercomputer, accessed through the Argonne Leadership Computing Facility (ALCF), a DOE Office of Science user facility. The ALCF is supported by DOE’s Advanced Scientific Computing Research program.
“The large-scale quantum circuit simulations efficiently utilized the DOE petascale supercomputer Polaris located at the ALCF. These results show how high-performance computing can complement and advance the field of quantum information science,” says Yuri Alexeev, a computational scientist at Argonne.
To take the first step toward practical realization of the speedup in the algorithm, the researchers demonstrated a small-scale implementation on Quantinuum’s System Model H1 and H2 trapped-ion quantum computers. Using algorithm-specific error detection, the team reduced the impact of errors on algorithmic performance by up to 65%.
“Our long-standing partnership with JPMorgan Chase led to this meaningful and noteworthy three-way research experiment that also brought in Argonne National Lab. The results could not have been achieved without the unprecedented and world leading quality of our H-Series Quantum Computer, which provides a flexible device for executing error-correcting and error-detecting experiments on top of gate fidelities that are years ahead of other quantum computers,” says Ilyas Khan, Founder and Chief Product Officer of Quantinuum.
About JPMorgan Chase
JPMorgan Chase & Co. (NYSE: JPM) is a leading financial services firm based in the United States of America (“U.S.”), with operations worldwide. JPMorgan Chase had $4.1 trillion in assets and $337 billion in stockholders’ equity as of March 31, 2024. With over 63,000 technologists globally and an annual tech spend of $17 billion, JPMorgan Chase is dedicated to improving the design, analytics, development, coding, testing and application programming that goes into creating high quality software and new products. Under the J.P. Morgan and Chase brands, the Firm serves millions of customers in the U.S., and many of the world’s most prominent corporate, institutional and government clients globally. Visit http://www.jpmorganchase.com/tech for more information.
About Argonne National Laboratory
Argonne National Laboratory seeks solutions to pressing national problems in science and technology by conducting leading-edge basic and applied research in virtually every scientific discipline. Argonne is managed by UChicago Argonne, LLC for the U.S. Department of Energy’s Office of Science.
About Quantinuum
Quantinuum, the world’s largest integrated quantum company, pioneers powerful quantum computers and advanced software solutions. Quantinuum’s technology drives breakthroughs in materials discovery, cybersecurity, and next-gen quantum AI. With almost 500 employees, including 370+ scientists and engineers, Quantinuum leads the quantum computing revolution across continents.
Quantinuum recently closed an equity fundraise anchored by JPMorgan Chase with additional participation from Mitsui & CO., Amgen and Honeywell, which remains the company’s majority shareholder, bringing the total capital raised by Quantinuum since inception to approximately $625 million.
The Honeywell trademark is used under license from Honeywell International Inc. Honeywell makes no representations or warranties with respect to this service.
About Quantinuum
Quantinuum, the world’s largest integrated quantum company, pioneers powerful quantum computers and advanced software solutions. Quantinuum’s technology drives breakthroughs in materials discovery, cybersecurity, and next-gen quantum AI. With over 500 employees, including 370+ scientists and engineers, Quantinuum leads the quantum computing revolution across continents.
Tokyo, Japan, August 19th, 2025 — Mitsui & Co., Ltd. (“Mitsui”), QSimulate, and Quantinuum today announced the launch of a new quantum-integrated chemistry platform, QIDO (Quantum-Integrated Discovery Orchestrator). This platform aims to reduce the time and cost of developing new drugs and materials. QIDO accelerates research and development through high-precision chemical reaction modeling and seamlessly combines the advantages of cutting-edge classical computing and quantum computing.
Built for commercial impact, QIDO streamlines complex quantum-classical hybrid workflows and helps companies make decisions earlier in the development process, contributing to a powerful competitive advantage in innovation. The platform is designed to support research across an array of chemistry-based fields, including advanced materials design, clean energy, and drug development.
Proprietary Technology Supporting QIDO
QIDO seamlessly integrates QSimulate's software “QSP Reaction,” which enables calculations on the scale of thousands of atoms using the highest precision classical quantum chemistry methods and techniques. QIDO also integrates with Quantinuum's “InQuanto" software, which interfaces with state-of-the-art quantum emulators and world-leading Quantinuum Systems hardware. InQuanto™ achieves up to 10 times higher accuracy in simulations of complex molecules and materials compared to open-source software.
- Makoto Koshida, General Manager, Quantum Innovation Department, Mitsui: “We take a market-needs-based approach, aiming to bridge the gap between providing practical features that help customers solve today's challenges and preparing them for the coming quantum era. This approach enables customers to maximize its benefits from day one when quantum technology comes into its own.”
- Toru Shiozaki, Ph.D., President & CEO, QSimulate: “Combining best-in-class quantum chemical simulation with deep quantum computing expertise, QIDO gives industrial chemists powerful, intuitive algorithms and tools to tackle complex chemical challenges with speed and accuracy. We are excited about the marriage between years of innovation in quantum chemistry automation and the future of quantum computation.”
- Dr. Rajeeb Hazra, President & CEO, Quantinuum: “Adding the benefits of chemical accuracy and computational efficiency of quantum-native simulations in applications of chemistry is a key step forward in revolutionizing the economics of discovery in several significant end markets, such as pharmaceuticals and energy. Quantinuum is proud to offer the industry's highest-performing quantum computers and widely used quantum chemistry software to enable this progress.”
QIDO Use Cases and Future Expansion
QIDO is launched together with a high-precision chemical reaction analysis module based on the so-called active space approach. Potential use cases are as follows:
- Catalysts and enzyme design: Simulating complex electron behavior to inform high-efficiency catalysts and enzymes design for cleaner energy, greener manufacturing, and advanced biocatalysis (useful in drug discovery, food processing, biofuel, etc.).
- Reaction mechanism elucidation: Enabling deeper understanding of complex chemical reaction pathways, including transient intermediates and excited states, for material stability, performance, and lifetime improvements.
- Battery efficiency and energy storage: Enhancing battery materials and performance for safer, longer-lasting, and higher-capacity energy storage.
- Sustainable materials and energy: Advancing energy-efficient materials, improving carbon capture and reuse, and supporting green ammonia and hydrogen production.
QIDO will gradually add new features to accelerate innovation in high-impact use cases, such as battery innovation and drug development. Innovation in these fields through quantum technology will be realized through 'co-creation' with our customers.
Feedback from Industry Leaders
As QIDO's exclusive distributor in Japan and a strategic partner with an eye toward future “co-creation,” Mitsui & Co. is leading domestic sales and distribution, laying the foundation for future global expansion. Prior to the general release of QIDO in the Japanese market, Mitsui & Co. conducted beta testing with three industry-leading companies.
- JSR Corporation: “The platform provided by QSimulate lowers the barriers to computation by simplifying input, automating error handling, and focusing output on necessary information, making it an integral tool in the daily workflows of synthetic organic chemists at JSR. With this platform now extended to support quantum chemistry calculations on quantum computers via InQuanto, it offers a path to an early quantum advantage.” – Yu-ya Ohnishi, Ph.D., Research Fellow & Deputy Director, R&D Technology & Digital Transformation Center, Materials Informatics Promotion Office
- Panasonic Holdings Corporation: “This platform provides users with a tool to intuitively perform chemical reaction simulations through a graphical user interface. In the anticipated era of large-scale fault-tolerant quantum computing, materials simulation is regarded as a promising application domain. Integrated with quantum computing, this platform is expected to offer opportunities for early-stage validation in preparation for future breakthroughs.” – Takahiro Ohgoe, Ph.D., Senior Lead Researcher, Green Innovation Center, Green Transformation Division
- Chugai Pharmaceutical: “This application offers an intuitive interface that combines user-friendly operability with clear, instantly interpretable result visualization—making reaction pathway exploration easier and more efficient than ever. At present, we recognize several technical challenges in applying the system to complex molecular calculations encountered in drug discovery and pharmaceutical research. As these challenges are steadily addressed, we expect this application to play a meaningful role in accelerating and optimizing the synthesis and process development of candidate molecules with complex chemical structures—ultimately contributing to innovation in drug discovery and the advancement of pharmaceutical development.” – Akihiko Arakawa, Ph.D., Data Science Group, Digital Solution Dept., Digital Transformation Unit
Notable Functions of QIDO
QIDO is equipped with various functions to streamline high-precision chemical modeling. This makes quantum chemistry technology, which was previously only available to experts, more accessible for use in industrial settings.
- Automatically identify reaction coordinates and transition states from specified reactants and products;
- Map strongly correlated systems to compact Hamiltonians using quantum embedding and automated active space selection techniques;
- Support customizable active spaces and computational methods to balance accuracy and cost;
- Provides optimized energy calculations for reactants, products, and transition states using quantum hardware and their emulators;
- Visualizes quantum circuits and reports the required quantum resources.
For purchases, trial applications, and other details, please visit: https://mitsui-q.com/en/qido/.
About Mitsui & Co., Ltd.
Mitsui & Co. is a global trading and investment company with a presence in more than 60 countries and a diverse business portfolio covering a wide range of industries.
The company identifies, develops, and grows its businesses in partnership with a global network of trusted partners including world leading companies, combining its geographic and cross-industry strengths to create long-term sustainable value for its stakeholders.
Mitsui has set three key strategic initiatives for its current Medium-term Management Plan: supporting industries to grow and evolve with stable supplies of resources and materials, and providing infrastructure; promoting a global transition to low-carbon and renewable energy; and empowering people to lead healthy lives through the delivery of quality healthcare and access to good nutrition.
For more information, please visit: https://www.mitsui.com/jp/en/index.html
About QSimulate
Founded in 2019 and headquartered in Boston, MA, QSimulate is a leader in quantum simulation technology for materials development and life sciences. The company offers a range of products and services designed to leverage the power of quantum mechanics to solve industrial-scale problems like never before.
For more information, please visit: https://qsimulate.com/
About Quantinuum
Quantinuum is the world leader in quantum computing. The company’s quantum systems deliver the highest performance across key industry benchmarks. Quantinuum’s over 550 employees, including 370+ scientists and engineers, across the US, UK, Germany, and Japan, are driving the quantum computing revolution.
For more information, please visit: https://www.quantinuum.com
Doha, Qatar, May 20th, 2025 — Invest Qatar, the Investment Promotion Agency of Qatar, has inked a strategic agreement with Quantinuum, the world leader in quantum computing and developer of the world’s highest-performing quantum computer. The partnership aims to strengthen Qatar’s quantum computing ecosystem by supporting Quantinuum’s recently announced expansion into the region, which was highlighted last week by the President of the United States during his historic state visit to Qatar.
Through this partnership, Invest Qatar will provide tailored support services to Quantinuum, including access to key stakeholders, sector-specific insights and opportunities for collaboration with local innovation and research institutions. Invest Qatar will also promote initiatives that drive quantum computing adoption and raise awareness of Quantinuum’s contributions to Qatar’s tech landscape. Through this partnership, Invest Qatar will support Quantinuum’s expansion into the country to apply quantum technologies for the benefit of key sectors in Qatar, while enhancing local research and development (R&D) capabilities, to create high-skilled jobs and train the next generation quantum workforce in Qatar. This includes facilitating connections with key stakeholders, enabling collaboration in R&D, and aligning with national initiatives aimed at advancing quantum technologies.
As part of the agreement, Quantinuum will play a central role in advancing Qatar’s quantum capabilities by launching a range of targeted initiatives, including knowledge-sharing platforms, educational seminars and technical workshops delivered by Quantinuum’s global experts. The partnership also envisions launching joint research projects with Qatari academic and research institutions, exploring opportunities for local integration of quantum technologies and facilitating access to Quantinuum’s cutting-edge quantum computing infrastructure. Additionally, internship opportunities will be offered to students from Qatar-based universities, providing direct experience in real-world quantum computing applications.
Commenting on the partnership, Sheikh Ali Alwaleed Al-Thani, CEO, Invest Qatar, said: “This partnership with Quantinuum reflects our continued commitment to positioning Qatar at the forefront of next-generation technologies. By combining global expertise with local ambition, we aim to cultivate a thriving quantum ecosystem that drives innovation, supports economic diversification and empowers future talent. We are pleased to work with Quantinuum to unlock the transformative potential of quantum computing for Qatar and the wider region.”
Dr. Rajeeb Hazra, President & CEO, Quantinuum, said: “Launching our presence in Qatar opens an exciting new chapter in a region ready to lead in quantum computing. Building on our recently announced expansion into the country through our joint venture with Al Rabban Capital, and our ongoing partnership with Hamad Bin Khalifa University, this collaboration with Invest Qatar reinforces our commitment to the growth of Qatar’s quantum computing ecosystem. As part of the deepening strategic ties between the U.S. and Qatar, we’re enabling direct access to our world-leading quantum hardware and software, creating value for academia and industry in Qatar while training the next generation of quantum developers and researchers to strengthen the region’s position as a global hub for advanced technologies.”
About Invest Qatar
The Investment Promotion Agency Qatar (Invest Qatar) is responsible for overseeing investment promotion activities, aimed at attracting foreign direct investment to Qatar. Established in 2019, Invest Qatar’s mission is to strengthen Qatar’s position as an ideal investment destination, while facilitating investments that foster economic diversification and development.
As the gateway to investment solutions, Invest Qatar connects investors to an integrated ecosystem of business and licensing platforms. The Agency partners with investors throughout their journey, from exploration and setup to expansion, ensuring their long-term growth by providing comprehensive insights into Qatar’s business landscape, sector-specific market knowledge and tailored investment facilitation.
For more information, please visit www.invest.qa
@InvestQatar | #InvestQatar
About Quantinuum
Quantinuum is the world leader in quantum computing. The company’s quantum systems deliver the highest performance across all industry benchmarks. Quantinuum’s over 550 employees, including 370+ scientists and engineers, across the US, UK, Germany, and Japan, are driving the quantum computing revolution.
For more information, please visit www.quantinuum.com
Doha, Qatar, May 14th, 2025 — Quantinuum, the world leader in quantum computing, is establishing a Qatari-incorporated Joint Venture with Al Rabban Capital, a division of Al Rabban Holding Company, one of Qatar’s most prominent companies. The Joint Venture will accelerate quantum computing adoption in Qatar and the region, strategically positioning the U.S. and Qatar as global leaders in the quantum revolution. This first of its kind quantum technology partnership was highlighted by the President of the United States during his historic state visit to Qatar.
The Joint Venture has three core objectives: enabling access to Quantinuum’s world-leading quantum technologies in the region; co-developing quantum computing applications tailored to regional needs in areas such as New Energy, Materials Discovery, Precision Medicine, Genomics, and Financial Services, with new opportunities emerging in the era of Generative Quantum AI (GenQAI); and, training the next generation of quantum computing developers in Qatar and the region.
Quantinuum is steadily expanding its global presence to meet the growing international demand for its technology and applications. The company’s expansion into the Gulf region, starting with Qatar, follows its successful growth across the U.S., U.K., Europe and Indo-Pacific. This Joint Venture reflects a shared commitment by the U.S. and Qatar to strengthen strategic ties, spur bilateral investment in future-defining industries, and foster technological leadership and shared prosperity.
Quantinuum’s Joint Venture with Al Rabban Capital builds on its partnership announced last year with Hamad Bin Khalifa University and the Qatar Center for Quantum Computing (QC2), Qatar’s premier quantum research hub.
“This is a defining moment in Qatar’s ambition to become a regional hub for advanced technologies like quantum computing,” said Abdulaziz Khalid Al Rabban, Chairman, Al Rabban Capital. “We're partnering with Quantinuum to deliver world-class quantum solutions, driving economic growth in Qatar and the region.”
“This Joint Venture demonstrates our shared vision to lead in transformative technologies,” said Dr. Rajeeb Hazra, President & CEO of Quantinuum. “Together with Al Rabban Capital, we’re accelerating the commercial adoption of quantum computing in Qatar and the region whilst serving U.S. and Qatari strategic interests.”
About Quantinuum
Quantinuum is the world leader in quantum computing. The company’s quantum systems deliver the highest performance across key industry benchmarks. Quantinuum’s over 550 employees, including 370+ scientists and engineers, across the US, UK, Germany, and Japan, are driving the quantum computing revolution.
For more information, please visit: https://www.quantinuum.com
About Al Rabban Capital
Al Rabban Capital (ARC) is a Qatari investment and advisory firm driving business growth across Qatar and the GCC. ARC enable market entry and expansion through joint ventures, strategic partnerships, and deep local insight. ARC supports both public and private sector initiatives with tailored, end-to-end solutions. Beyond capital, ARC provide strategic guidance, governance, and access to a robust regional network. ARC’s focus includes AI, quantum tech, healthcare, and sustainability, with a commitment to impactful growth.
For more information, please visit: https://www.alrabbancapital.com