By chemists for chemists
Introducing InQuanto™ 2.0
When we launched InQuanto™, our computational chemistry platform for quantum computing, we explained that its origins lay at least as much with our industrial partners as it did with us. We revealed that its development was the culmination of many important scientific collaborations with some of the world’s leading industrial names in energy, automotive, pharmaceuticals, industrial materials, and other sectors.
Today, we announce the next version of our state-of-the-art platform. Just as before, it is important to us that InQuanto 2.0, while being more versatile, more extensible, and more applicable for those who have not yet explored the use of quantum computers, is the result of precisely the same spirit of collaboration.
In close collaboration with our industrial partners, we have designed, developed, and discovered methods using InQuanto for exploring the application of near-term quantum technology to material and molecular problems that remain challenging or intractable for even the most powerful classical computers.
What’s inside InQuanto 2.0?
InQuanto continues to be built around the latest quantum algorithms, advanced subroutines, and chemistry-specific noise-mitigation techniques. In the new version, we have added new features to enhance efficiency, such as new protocol classes that can speed up vector calculations by an order of magnitude, and integral operator classes that exploit symmetries and can reduce memory requirements.
We have introduced new tools for developing custom ansätze, new embedding techniques and novel hybrid methods to improve efficiency and precision, which in some cases have only recently been described in the scientific literature. And these rapid advances are supported by new ways for computational chemists to build InQuanto into their workflow, whether that is by improving visualization and interoperability with other chemistry packages, or by demonstrating the ability to run it in the cloud, for example, through a recent demonstration with Amazon Braket.
The most exciting progress, of course, is reflected in the diverse work of our partners. We know that some of the work being done today will be reflected in future methods and techniques incorporated into InQuanto, fulfilling the ever more advanced needs of our partners tomorrow.
Please book a demonstration of InQuanto 2.0 today.
InQuanto 2.0 brings together a range of new features that continue to make it the right choice for computational chemists on quantum computers:
Efficiency
- Workflow improvements in protocol classes for more efficient small test calculations — up to 10x speed-ups in some state vector calculations
- Symmetry-exploiting integral operator classes for efficient handling of the two-electron integral for a chemistry Hamiltonian using ~50% less memory
- Optimized computables for n-particle reduced density matrices
Algorithms
- Wide range of restructured ansätze to support multi-reference calculations to enable new types of variational quantum algorithms — with improved custom ansatz development tools
- Generalised variational quantum solvers to perform imaginary and real-time evolution simulations
- Added Fragment Molecular Orbital embedding method
- New QRDM-NEVPT2 method to measure 4-particle reduced density matrices and add corrections to VQE energy
User Experience
- FCIDUMP read/write for improved integration with other quantum chemistry packages
- Unit cell visualization extensions, and support for trotterization in the operator level
- Improved resource cost estimation on H-Series quantum computers, Powered by Honeywell
What to read next:
Research case study:
Ford battery researchers used InQuanto™ to study how quantum computers could be used to model lithium-ion batteries.
About Quantinuum
Quantinuum, the world’s largest integrated quantum company, pioneers powerful quantum computers and advanced software solutions. Quantinuum’s technology drives breakthroughs in materials discovery, cybersecurity, and next-gen quantum AI. With over 500 employees, including 370+ scientists and engineers, Quantinuum leads the quantum computing revolution across continents.
If we are to create ‘next-gen’ AI that takes full advantage of the power of quantum computers, we need to start with quantum native transformers. Today we announce yet again that Quantinuum continues to lead by demonstrating concrete progress — advancing from theoretical models to real quantum deployment.
The future of AI won't be built on yesterday’s tech. If we're serious about creating next-generation AI that unlocks the full promise of quantum computing, then we must build quantum-native models—designed for quantum, from the ground up.
Around this time last year, we introduced Quixer, a state-of-the-art quantum-native transformer. Today, we’re thrilled to announce a major milestone: one year on, Quixer is now running natively on quantum hardware.
Why this matters: Quantum AI, born native
This marks a turning point for the industry: realizing quantum-native AI opens a world of possibilities.
Classical transformers revolutionized AI. They power everything from ChatGPT to real-time translation, computer vision, drug discovery, and algorithmic trading. Now, Quixer sets the stage for a similar leap — but for quantum-native computation. Because quantum computers differ fundamentally from classical computers, we expect a whole new host of valuable applications to emerge.
Achieving that future requires models that are efficient, scalable, and actually run on today’s quantum hardware.
That’s what we’ve built.
What makes Quixer different?
Until Quixer, quantum transformers were the result of a brute force “copy-paste” approach: taking the math from a classical model and putting it onto a quantum circuit. However, this approach does not account for the considerable differences between quantum and classical architectures, leading to substantial resource requirements.
Quixer is different: it’s not a translation – it's an innovation.
With Quixer, our team introduced an explicitly quantum transformer, built from the ground up using quantum algorithmic primitives. Because Quixer is tailored for quantum circuits, it's more resource efficient than most competing approaches.
As quantum computing advances toward fault tolerance, Quixer is built to scale with it.
What’s next for Quixer?
We’ve already deployed Quixer on real-world data: genomic sequence analysis, a high-impact classification task in biotech. We're happy to report that its performance is already approaching that of classical models, even in this first implementation.
This is just the beginning.
Looking ahead, we’ll explore using Quixer anywhere classical transformers have proven to be useful; such as language modeling, image classification, quantum chemistry, and beyond. More excitingly, we expect use cases to emerge that are quantum-specific, impossible on classical hardware.
This milestone isn’t just about one model. It’s a signal that the quantum AI era has begun, and that Quantinuum is leading the charge with real results, not empty hype.
Stay tuned. The revolution is only getting started.
Our team is participating in ISC High Performance 2025 (ISC 2025) from June 10-13 in Hamburg, Germany!
As quantum computing accelerates, so does the urgency to integrate its capabilities into today’s high-performance computing (HPC) and AI environments. At ISC 2025, meet the Quantinuum team to learn how the highest performing quantum systems on the market, combined with advanced software and powerful collaborations, are helping organizations take the next step in their compute strategy.
Quantinuum is leading the industry across every major vector: performance, hybrid integration, scientific innovation, global collaboration and ease of access.
- Our industry-leading quantum computer holds the record for performance with a Quantum Volume of 2²³ = 8,388,608 and the highest fidelity on a commercially available QPU available to our users every time they access our systems.
- Our systems have been validated by a #1 ranking against competitors in a recent benchmarking study by Jülich Research Centre.
- We’ve laid out a clear roadmap to reach universal, fully fault-tolerant quantum computing by the end of the decade and will launch our next-generation system, Helios, later this year.
- We are advancing real-world hybrid compute with partners such as RIKEN, NVIDIA, SoftBank, STFC Hartree Center and are pioneering applications such as our own GenQAI framework.
Exhibit Hall
From June 10–13, in Hamburg, Germany, visit us at Booth B40 in the Exhibition Hall or attend one of our technical talks to explore how our quantum technologies are pushing the boundaries of what’s possible across HPC.
Presentations & Demos
Throughout ISC, our team will present on the most important topics in HPC and quantum computing integration—from near-term hybrid use cases to hardware innovations and future roadmaps.
Multicore World Networking Event
- Monday, June 9 | 7:00pm – 9:00 PM at Hofbräu Wirtshaus Esplanade
In partnership with Multicore World, join us for a Quantinuum-sponsored Happy Hour to explore the present and future of quantum computing with Quantinuum CCO, Dr. Nash Palaniswamy, and network with our team.
Register here
H1 x CUDA-Q Demonstration
- All Week at Booth B40
We’re showcasing a live demonstration of NVIDIA’s CUDA-Q platform running on Quantinuum’s industry-leading quantum hardware. This new integration paves the way for hybrid compute solutions in optimization, AI, and chemistry.
Register for a demo
HPC Solutions Forum
- Wednesday, June 11 | 2:20 – 2:40 PM
“Enabling Scientific Discovery with Generative Quantum AI” – Presented by Maud Einhorn, Technical Account Executive at Quantinuum, discover how hybrid quantum-classical workflows are powering novel use cases in scientific discovery.
See You There!
Whether you're exploring hybrid solutions today or planning for large-scale quantum deployment tomorrow, ISC 2025 is the place to begin the conversation.
We look forward to seeing you in Hamburg!
Quantinuum has once again raised the bar—setting a record in teleportation, and advancing our leadership in the race toward universal fault-tolerant quantum computing.
Last year, we published a paper in Science demonstrating the first-ever fault-tolerant teleportation of a logical qubit. At the time, we outlined how crucial teleportation is to realize large-scale fault tolerant quantum computers. Given the high degree of system performance and capabilities required to run the protocol (e.g., multiple qubits, high-fidelity state-preparation, entangling operations, mid-circuit measurement, etc.), teleportation is recognized as an excellent measure of system maturity.
Today we’re building on last year’s breakthrough, having recently achieved a record logical teleportation fidelity of 99.82% – up from 97.5% in last year’s result. What’s more, our logical qubit teleportation fidelity now exceeds our physical qubit teleportation fidelity, passing the break-even point that establishes our H2 system as the gold standard for complex quantum operations.
This progress reflects the strength and flexibility of our Quantum Charge Coupled Device (QCCD) architecture. The native high fidelity of our QCCD architecture enables us to perform highly complex demonstrations like this that nobody else has yet to match. Further, our ability to perform conditional logic and real-time decoding was crucial for implementing the Steane error correction code used in this work, and our all-to-all connectivity was essential for performing the high-fidelity transversal gates that drove the protocol.
Teleportation schemes like this allow us to “trade space for time,” meaning that we can do quantum error correction more quickly, reducing our time to solution. Additionally, teleportation enables long-range communication during logical computation, which translates to higher connectivity in logical algorithms, improving computational power.
This demonstration underscores our ongoing commitment to reducing logical error rates, which is critical for realizing the promise of quantum computing. Quantinuum continues to lead in quantum hardware performance, algorithms, and error correction—and we’ll extend our leadership come the launch of our next generation system, Helios, in just a matter of months.