By chemists for chemists

Introducing InQuanto™ 2.0

December 13, 2022

When we launched InQuanto™, our computational chemistry platform for quantum computing, we explained that its origins lay at least as much with our industrial partners as it did with us. We revealed that its development was the culmination of many important scientific collaborations with some of the world’s leading industrial names in energy, automotive, pharmaceuticals, industrial materials, and other sectors.

Today, we announce the next version of our state-of-the-art platform. Just as before, it is important to us that InQuanto 2.0, while being more versatile, more extensible, and more applicable for those who have not yet explored the use of quantum computers, is the result of precisely the same spirit of collaboration.

In close collaboration with our industrial partners, we have designed, developed, and discovered methods using InQuanto for exploring the application of near-term quantum technology to material and molecular problems that remain challenging or intractable for even the most powerful classical computers.

What’s inside InQuanto 2.0?

InQuanto continues to be built around the latest quantum algorithms, advanced subroutines, and chemistry-specific noise-mitigation techniques. In the new version, we have added new features to enhance efficiency, such as new protocol classes that can speed up vector calculations by an order of magnitude, and integral operator classes that exploit symmetries and can reduce memory requirements.

We have introduced new tools for developing custom ansätze, new embedding techniques and novel hybrid methods to improve efficiency and precision, which in some cases have only recently been described in the scientific literature. And these rapid advances are supported by new ways for computational chemists to build InQuanto into their workflow, whether that is by improving visualization and interoperability with other chemistry packages, or by demonstrating the ability to run it in the cloud, for example, through a recent demonstration with Amazon Braket.

The most exciting progress, of course, is reflected in the diverse work of our partners. We know that some of the work being done today will be reflected in future methods and techniques incorporated into InQuanto, fulfilling the ever more advanced needs of our partners tomorrow.

Please book a demonstration of InQuanto 2.0 today.

InQuanto 2.0 brings together a range of new features that continue to make it the right choice for computational chemists on quantum computers:

Efficiency

  • Workflow improvements in protocol classes for more efficient small test calculations — up to 10x speed-ups in some state vector calculations
  • Symmetry-exploiting integral operator classes for efficient handling of the two-electron integral for a chemistry Hamiltonian using ~50% less memory
  • Optimized computables for n-particle reduced density matrices

Algorithms

  • Wide range of restructured ansätze to support multi-reference calculations to enable new types of variational quantum algorithms — with improved custom ansatz development tools
  • Generalised variational quantum solvers to perform imaginary and real-time evolution simulations
  • Added Fragment Molecular Orbital embedding method
  • New QRDM-NEVPT2 method to measure 4-particle reduced density matrices and add corrections to VQE energy

User Experience

  • FCIDUMP read/write for improved integration with other quantum chemistry packages
  • Unit cell visualization extensions, and support for trotterization in the operator level
  • Improved resource cost estimation on H-Series quantum computers, Powered by Honeywell 
What to read next:

Research case study:
Ford battery researchers used InQuanto™ to study how quantum computers could be used to model lithium-ion batteries.

About Quantinuum

Quantinuum, the world’s largest integrated quantum company, pioneers powerful quantum computers and advanced software solutions. Quantinuum’s technology drives breakthroughs in materials discovery, cybersecurity, and next-gen quantum AI. With over 500 employees, including 370+ scientists and engineers, Quantinuum leads the quantum computing revolution across continents. 

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June 10, 2026
Quantinuum's Fault-Tolerance Advantage: Turning Quantum Reliability into Commercial Usefulness
  • Quantinuum continues its progress toward fault-tolerant quantum computing, with a series of peer-reviewed breakthroughs in fault-tolerant operations.
  • Our progress is not only scientific; it is commercial. By improving logical-qubit reliability and encoding efficiency, Quantinuum is reducing the resource overhead required to scale its quantum computers toward commercially useful workloads.
  • These results were achieved on commercial Quantinuum hardware, reinforcing that our architecture is not just setting new standards, but building a practical foundation for customers, partners, and researchers preparing for the fault-tolerant era.

Fault-tolerant quantum computing is the threshold the industry must cross before quantum computers can solve the hardest, highest-value problems with confidence. To be commercially useful at scale, the question is not simply who can build more qubits. It is who can build reliable, efficient, scalable systems that reduce technical risk and accelerate the path to commercial usefulness.

Quantinuum is progressing on that path.

Last year, in partnership with Microsoft, we published a breakthrough in logical computing, demonstrating logical qubits that outperformed their physical counterparts by a factor of 800. We are proud to announce that this work is now being published in Nature, one of the most highly regarded scientific journals in the world.  

This work highlights our leading fidelities, as shown in Table 1:

Since then, we’ve accelerated our efforts to reach large-scale fault tolerance and advanced what we believe to be the core building blocks of fault-tolerant quantum computing, from logical-qubit teleportation and multiple error-correction breakthroughs to one of the first meaningful computations using logical qubits. Importantly, these results were achieved on commercial Quantinuum hardware, demonstrating not just scientific progress, but a practical and efficient path toward scalable, customer-ready fault tolerance.

A Recap of Our Recent Technical Progress

Since the work with Microsoft, we achieved a milestone years ahead of schedule, demonstrating high-fidelity teleportation of a logical qubit, which was published in Science, one of the world’s most prestigious journals. Later, we beat our own record in this crucial fault tolerance milestone, thanks to continued improvements to our System Model H2’s fidelity.

Then, a series of results demonstrating more error-correcting milestones (and codes):

Recently, we topped ourselves yet again by performing one of the first meaningful computations with logical qubits – exploring key questions in materials and magnetism, using logical qubits with better error rates than their physical counterparts. This result also includes a leading “encoding rate” squeezing 48 logical qubits out of just 98 physical qubits, emphasizing how our architecture helps to support large scale fault tolerance without enormous resource costs.

It is worth noting that all these results were achieved on our commercial hardware, not on one-off laboratory test-stands – reflecting the performance that we are able to deliver to our customers.

We also did crucial theoretical work, exploring new options for error correction that can reduce resource requirements, time to solution, and shorten the timeline to large scale fault tolerance.

Commercial Implications and the Road Ahead

We believe the commercial implication is clear: Quantinuum is reducing the uncertainty around the path to fault-tolerant quantum computing. Our architecture, hardware fidelity, full-stack control, and error-correction progress are converging into a practical roadmap for systems that can support valuable scientific and commercial workloads.

For those evaluating when quantum computing will become strategically relevant, we believe the signal is also increasingly clear: the fault-tolerant era is no longer a distant concept. It is becoming an engineering reality, and Quantinuum is leading the way.

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May 7, 2026
Denmark Strengthens its Quantum Leadership with Quantinuum Helios
  • University of Southern Denmark (SDU) to use Quantinuum Helios, supported by the Danish e-Infrastructure Consortium (DeiC)
  • Access to Helios enables SDU to test and refine fault-tolerant algorithms and error-correction codes under realistic hardware conditions
  • The collaboration supports at a scale of 48 logical qubits, positioning Denmark at the forefront of scalable, practical quantum computing
  • Researchers exploring the scientific foundations for future development of applications in fields including pharmaceuticals, finance, and defense

Progress in quantum computing is measured by hardware advances plus the algorithms and quantum error-correction codes that turn quantum systems into useful computational tools.

Thanks to recent hardware advances, researchers are increasingly sharpening their tools to probe the performance of quantum algorithms and understand how they behave in realistic conditions – where stability, system architecture and algorithm design all shape performance.

A new Denmark-based collaboration between the University of Southern Denmark (SDU), Quantinuum, and the Danish e-Infrastructure Consortium (DeiC) will utilize Quantinuum Helios. Researchers at the SDU’s Centre for Quantum Mathematics, led by Jørgen Ellegaard Andersen, will use Helios to pursue research into topological quantum computing.

Their work could help explain how and why successful quantum algorithms perform as they do, informing the development of high-performance algorithms suited to emerging quantum systems. They’re exploring the scientific foundations that support future quantum applications across areas including pharmaceuticals, finance, and defense.

“We are thrilled to gain access to Quantinuum’s high-fidelity Helios system. This collaboration gives us a unique opportunity to test the limits of our algorithms and evaluate system performance, while advancing fundamental research and laying the foundation for future applications.”

— Professor Jørgen Ellegaard Andersen, Director of the Centre for Quantum Mathematics at University of Southern Denmark
Why topological methods matter

Topological quantum computing is an area of research that connects quantum computation with deep mathematical structures. It includes the study of error correcting codes known as surface codes that encode quantum information in the global properties of systems of logical qubits.

The research team will explore how these codes behave, and how they may support the development of fault-tolerant quantum algorithms in practical implementations under realistic conditions.

This distinction between theory and practical implementation matters. In theory, topological approaches offer a rich framework for designing algorithms and error-correcting codes. In practice, researchers need to understand how those ideas perform when implemented on real systems, where questions of noise, stability, overhead, and scaling become central. The collaboration will allow the SDU team to investigate these questions directly.

New ways to benchmark quantum processors

Beyond individual algorithms and codes, the research will also develop tools for benchmarking quantum processors. The goal is to develop new ways to characterize fidelity and stability in regimes that can be difficult to access.

The team will also explore hybrid quantum–classical approaches, including machine-learning techniques assisted by quantum hardware, to study the mathematical structures at the heart of topological quantum computing. This work reflects a broader field of research in which quantum and classical methods are used together, each contributing to parts of a computational problem.

Strengthening Denmark’s quantum ecosystem

The collaboration reflects the growing role of national quantum infrastructure in supporting research and talent development. Denmark has a long tradition of scientific innovation, and this collaboration is intended to support the country’s continued development in quantum technology.

The initiative is supported by DeiC, which played a central role in securing funding and enabling access to Quantinuum’s systems. DeiC has been assigned a particular role in developing and coordinating quantum infrastructure initiatives for the benefit of universities and industry, operating without its own commercial, sectoral, or geographical interests. This includes securing dedicated access to quantum computers, producing advisory services and supporting the development of new talent in the Danish quantum sector.

“DeiC’s special effort to secure funding and access for this research initiative is rooted in our organization’s role in relation to the Danish Government’s strategy for quantum technology.”

— Henrik Navntoft Sønderskov, Head of Quantum at Danish e-Infrastructure Consortium

This collaboration promises to accelerate the development of practical algorithms. It is grounded in fundamental science – but its focus is practical: discovering and testing mathematical approaches to topological quantum computing that can be implemented, evaluated, and improved on real quantum hardware.

That work requires both theoretical insight and access to a system such as Helios capable of supporting meaningful scientific work.

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March 25, 2026
Celebrating Our First Annual Q-Net Connect!

This month, Quantinuum welcomed its global user community to the first-ever Q-Net Connect, an annual forum designed to spark collaboration, share insights, and accelerate innovation across our full-stack quantum computing platforms. Over two days, users came together not only to learn from one another, but to build the relationships and momentum that we believe will help define the next chapter of quantum computing.

Q-Net Connect 2026 drew over 170 attendees from around the world to Denver, Colorado, including representatives from commercial enterprises and startups, academia and research institutions, and the public sector and non-profits - all users of Quantinuum systems.  

The program was packed with inspiring keynotes, technical tracks, and customer presentations. Attendees heard from leaders at Quantinuum, as well as our partners at NVIDIA, JPMorganChase and BlueQubit; professors from the University of New Mexico, the University of Nottingham and Harvard University; national labs, including NIST, Oak Ridge National Laboratory, Sandia National Laboratories and Los Alamos National Laboratory; and other distinguished guests from across the global quantum ecosystem.

Congratulations to Q-Net Connect 2026 Award Recipients! 

The mission of the Quantinuum Q-Net user community is to create a space for shared learning, collaboration and connection for those who adopt Quantinuum’s hardware, software and middleware platform. At this year’s Q-Net Connect, we awarded four organizations who made notable efforts to champion this effort. 

  • JPMorganChase received the ‘Guppy Adopter Award’ for their exemplary adoption of our quantum programming language, Guppy, in their research workflows. 
  • Phasecraft, a UK and US-based quantum algorithms startup, received the ‘Rising Star’ award for demonstrating exceptional early impact and advancing science using Quantinuum hardware, which they published in a December 2025 paper.
  • Qedma, a quantum software startup, received the ‘Startup Partner Engagement’ award for their sustained engagement with Quantinuum platforms dating back to our first commercially deployed quantum computer, H1.
  • Anna Dalmasso from the University of Nottingham received our ‘New Student Award’ for her impressive debut project on Quantinuum hardware and for delivering outstanding results as a new Q-Net student user. 

Congratulations, again, and thank you to everyone who contributed to the success of the first Q-Net Connect!

Become a Q-Net Member

Q-Net offers year‑round support through user access, developer tools, documentation, trainings, webinars, and events. Members enjoy many exclusive benefits, including being the first to hear about exclusive content, publications and promotional offers.

By joining the community, you will be invited to exclusive gatherings to hear about the latest breakthroughs and connect with industry experts driving quantum innovation. Members also get access to Q‑Net Connect recordings and stay connected for future community updates.

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